Protein Info for H281DRAFT_00802 in Paraburkholderia bryophila 376MFSha3.1

Annotation: Nucleoside-diphosphate-sugar epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 348 PF01370: Epimerase" amino acids 4 to 251 (248 residues), 162.8 bits, see alignment E=1.4e-51 PF16363: GDP_Man_Dehyd" amino acids 5 to 329 (325 residues), 94.7 bits, see alignment E=1.2e-30 PF01073: 3Beta_HSD" amino acids 5 to 159 (155 residues), 25.6 bits, see alignment E=8.9e-10

Best Hits

KEGG orthology group: None (inferred from 99% identity to bpy:Bphyt_1798)

Predicted SEED Role

"UDP-glucuronic acid oxidase (UDP-4-keto-hexauronic acid decarboxylating) (EC 1.1.1.305)" (EC 1.1.1.305)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.305

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MC16 at UniProt or InterPro

Protein Sequence (348 amino acids)

>H281DRAFT_00802 Nucleoside-diphosphate-sugar epimerase (Paraburkholderia bryophila 376MFSha3.1)
MKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTERLGDLINHERMHFFEGDITINKE
WVEYHVKKCDVILPLVAIATPATYVKQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSE
VYGMCTDEQFDPEESQLSYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIG
PGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGAQKRAFTDIDDGIGALMKIIENKD
GVATGKIYNIGNPTNNFSVRELAHKMLTLAAEFPEYADTAKKVQLVETSSGAYYGAGYQD
VQNRVPKIDNTMQELGWAPKSTFDEALRKIFEAYRGHVGEARALVEQQ