Protein Info for H281DRAFT_00699 in Paraburkholderia bryophila 376MFSha3.1

Annotation: RND family efflux transporter, MFP subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 359 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details TIGR01730: efflux transporter, RND family, MFP subunit" amino acids 39 to 348 (310 residues), 225.5 bits, see alignment E=4.2e-71 PF16576: HlyD_D23" amino acids 47 to 263 (217 residues), 85.3 bits, see alignment E=5.6e-28 PF13533: Biotin_lipoyl_2" amino acids 50 to 96 (47 residues), 28.2 bits, see alignment 1.9e-10 PF13437: HlyD_3" amino acids 160 to 254 (95 residues), 41.8 bits, see alignment E=2.4e-14

Best Hits

KEGG orthology group: None (inferred from 84% identity to bph:Bphy_3539)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MHT8 at UniProt or InterPro

Protein Sequence (359 amino acids)

>H281DRAFT_00699 RND family efflux transporter, MFP subunit (Paraburkholderia bryophila 376MFSha3.1)
MACSAILLSACHQREVVAPAAKPVVARVVRPDGRIPGESLPAQVEARYSTTLSFRVGGKI
TERRVRIGDTVKAGQTVALLDPTDLQNNLVSARAQLDAAEHRLVFAKQQLDRDEAQAHAN
LIAPAQLEQTQDAYATALAQRNSSLAQMALAADHLRYATLAADHDGVVTSEDANTGQNVQ
ATQAVYHIDWTGDVDIVCDAPERVVNSLKAGSKARVTLPALPGKSFEASVREVSAAADQE
SRTWRVKLTLAAASPEVRLGMTANVAFDSVQGNAVGQTFTLPVTALFHRGENPAVWVVRS
GSDTLELRPVTIQRYEERTVSIGSGLHDGERVILQGVHAVSSGQHVQVVPPLHPEDFPS