Protein Info for H281DRAFT_00647 in Paraburkholderia bryophila 376MFSha3.1

Annotation: 2-keto-3-deoxygluconate permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 326 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 44 to 65 (22 residues), see Phobius details amino acids 78 to 98 (21 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details amino acids 142 to 164 (23 residues), see Phobius details amino acids 170 to 190 (21 residues), see Phobius details amino acids 197 to 217 (21 residues), see Phobius details amino acids 223 to 246 (24 residues), see Phobius details amino acids 256 to 278 (23 residues), see Phobius details amino acids 289 to 311 (23 residues), see Phobius details PF03812: KdgT" amino acids 6 to 314 (309 residues), 394 bits, see alignment E=2.6e-122

Best Hits

Swiss-Prot: 66% identical to KDGT_CARHZ: 2-keto-3-deoxygluconate permease (kdgT) from Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901)

KEGG orthology group: K02526, 2-keto-3-deoxygluconate permease (inferred from 96% identity to bgf:BC1003_0578)

MetaCyc: 54% identical to 2-dehydro-3-deoxy-D-gluconate:H+ symporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-113

Predicted SEED Role

"2-keto-3-deoxygluconate permease (KDG permease)" in subsystem D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M9P4 at UniProt or InterPro

Protein Sequence (326 amino acids)

>H281DRAFT_00647 2-keto-3-deoxygluconate permease (Paraburkholderia bryophila 376MFSha3.1)
MAQIHIKRGIERVPGGMMIVPLLLGALVATFLPGMPKFFGSFTNALFTGALPILAVFYVC
MGASIDVKATPYLLKKGGALFVTKVGAAIVIGVVMGHFLGEQPISSGLFAGLSTLAVVAA
MNDTNGGLYMALMGQYGRSEDVGAYTIMSLESGPFLTMVTLGVAGLSAFPWPTLVGSILP
LVFGMLLGNLDREMRAFLGKAVPVMIPFFALALGASLDLHKVWQAGILGIGLGIAVVIVT
GIPLYLADRLTGGTGVAGVAAANTAGNAAAVPALIAAANPVYSEAAKSATLLVAACVVVT
AILSPILTAAVAKRVQLRREAGELAR