Protein Info for H281DRAFT_00482 in Paraburkholderia bryophila 376MFSha3.1

Annotation: molecular chaperone HscA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 623 TIGR01991: Fe-S protein assembly chaperone HscA" amino acids 21 to 622 (602 residues), 926.2 bits, see alignment E=4.3e-283 PF00012: HSP70" amino acids 21 to 606 (586 residues), 599.2 bits, see alignment E=7.5e-184 PF06723: MreB_Mbl" amino acids 119 to 378 (260 residues), 56.8 bits, see alignment E=1.8e-19

Best Hits

Swiss-Prot: 85% identical to HSCA_BURCM: Chaperone protein HscA homolog (hscA) from Burkholderia ambifaria (strain ATCC BAA-244 / AMMD)

KEGG orthology group: K04044, molecular chaperone HscA (inferred from 96% identity to bug:BC1001_2288)

Predicted SEED Role

"Chaperone protein HscA" in subsystem Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MA47 at UniProt or InterPro

Protein Sequence (623 amino acids)

>H281DRAFT_00482 molecular chaperone HscA (Paraburkholderia bryophila 376MFSha3.1)
MALLQISEPGMAPAPHQRRLAVGIDLGTTNSLVAAVRSGVPDVLPDEDGHVLLPSVVRYL
EKGGRRIGRAAKAEAATDPRNTIVSVKRFMGRGKAEVEGAENAPYDFIDAPGMVQIRTVD
GVKSPVEVSAEILATLRQRAEDTLGDELVGAVITVPAYFDEAQRQATKDAARLAGLNVLR
LLNEPTAAAIAYGLDNGSEGLYAVYDLGGGTFDLSILKLTKGVFEVLAAGGDSALGGDDF
DHALYRHVLEQAGIAPKTLAPEDVRLLLDSVRTTKEALSDAPEVTLAVTLSNGARIDLTI
DEATFEAITQALVQRTLGPTKKALRDAKVTTKEIKGVVLVGGATRMPVIRRAVESFFGQP
PLTNLDPDQVVALGAAIQADLLAGNRGADGDDWLLLDVIPLSLGVETMGGLTEKIIPRNS
TIPVARAQDFTTFKDGQTAMAIHVVQGERELVSDCRSLARFELRGIPPMAAGAARIRVTY
QVDADGLLSVFARELGSGVEASVVVKPSYGLADNDIARMLEDSFSTAEVDMRARALREAQ
VEARRLVEATDAALAADAELLDDSERAELDALLTGLRNVAGSDDVDAIEAATKKLAEGTD
EFAARRMNKGIRRALAGRKLDEI