Protein Info for H281DRAFT_00473 in Paraburkholderia bryophila 376MFSha3.1

Annotation: iron-sulfur cluster-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 471 transmembrane" amino acids 34 to 48 (15 residues), see Phobius details amino acids 399 to 418 (20 residues), see Phobius details TIGR00273: iron-sulfur cluster-binding protein" amino acids 18 to 452 (435 residues), 447.2 bits, see alignment E=3.2e-138 PF02589: LUD_dom" amino acids 67 to 292 (226 residues), 162.6 bits, see alignment E=3.2e-51 PF13183: Fer4_8" amino acids 306 to 374 (69 residues), 48.6 bits, see alignment E=3.4e-16 PF13534: Fer4_17" amino acids 309 to 374 (66 residues), 28.4 bits, see alignment E=6.6e-10 PF11870: LutB_C" amino acids 392 to 466 (75 residues), 39.1 bits, see alignment E=2.9e-13

Best Hits

Swiss-Prot: 44% identical to LUTB_GEOSW: Lactate utilization protein B (lutB) from Geobacillus sp. (strain WCH70)

KEGG orthology group: None (inferred from 96% identity to bgf:BC1003_1161)

Predicted SEED Role

"Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF" in subsystem L-rhamnose utilization or Lactate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M978 at UniProt or InterPro

Protein Sequence (471 amino acids)

>H281DRAFT_00473 iron-sulfur cluster-binding protein (Paraburkholderia bryophila 376MFSha3.1)
MQVQSMQFKARAGQKLADQRLQQNLTKLSTKFVSARAVAMTAIDFAATRAALKERRNRAL
ENLDVWLETFEREANRRGVTVLFAETTQEAARLVGDIARRHDVKKVIKTKSMVTEEMRLN
EVLGQMGVQSIETDLGEYILQINGNEPPSHIIAPVVHKDKDEIADLFAKTHGRPRLTEIP
DMTLEARQVLRPHFLSADMGVTGGNFVIAETGSVVLVTNEGNEGMCTVMPRVHVAVTGIE
KVLPTLEDLATAMRLLPRSATGQTTSNYFSLLTGPRGEGDQDGPEHMYVVLVDGGRTGLI
GGDFQEMLRCIRCGACMNHCPVYQKVGGHAYGWVYPGPMGSVLTPSYVGLDKALDLPQAA
TLCGECNSVCPVGIPLSDLLRKLREKQVERRLRPWKERAGLAVWGFMALHPGMYALVTKL
AVRVLERLGGSNRSIAKLPLAGAGWTDTRDMPAPVGRTFRELYAAQRSHIG