Protein Info for H281DRAFT_00460 in Paraburkholderia bryophila 376MFSha3.1
Annotation: cytosine deaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 47% identical to CODA_ECOLI: Cytosine deaminase (codA) from Escherichia coli (strain K12)
KEGG orthology group: K01485, cytosine deaminase [EC: 3.5.4.1] (inferred from 96% identity to bpy:Bphyt_2598)MetaCyc: 47% identical to cytosine/isoguanine deaminase (Escherichia coli K-12 substr. MG1655)
Cytosine deaminase. [EC: 3.5.4.1]; RXN0-6708 [EC: 3.5.4.1]
Predicted SEED Role
"Cytosine deaminase (EC 3.5.4.1)" (EC 3.5.4.1)
MetaCyc Pathways
- pyrimidine nucleobases salvage II (2/2 steps found)
- pyrimidine ribonucleosides salvage III (1/2 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.5.4.1
Use Curated BLAST to search for 3.5.4.1
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5MA28 at UniProt or InterPro
Protein Sequence (430 amino acids)
>H281DRAFT_00460 cytosine deaminase (Paraburkholderia bryophila 376MFSha3.1) MDLIIRHAMLPKSIAPQAGQPLDIGIEAGRIVAVEPNLAAAAREEIDAAGSLVTPPFVDP HFHMDATLSYGLPRVNASGTLLEGIALWGELKPQLTQDALIERAMQYCDWAVARGLLAIR SHVDVCDPRLLAVEALVEVKRRVAPYLDLQLVAFPQDGVLRSPGAFENLKRSIAMGVDVV GGIPHFERTMADGAQSVRMLCEYAAEQGLRVDMHCDESDDPMSRHIETLAAETQRLGLHG RVTGSHLTSMHSMDNYYVSKLLPLMRESGVAAIANPLINITLQGRSDTYPKRRGMTRVPE MMAAGINVAFGHDCVMDPWYSLGSGDMLEVAHMGLHVAQMTGVEGMHACFDAVTVNAARI LGLEGYGVAPGCAANLVLLDARDPVEAIRLRAARLAVVSRGKVVSRAPAVRAALSLEGRP AEVDFKLHRG