Protein Info for H281DRAFT_00429 in Paraburkholderia bryophila 376MFSha3.1

Annotation: L-fuconate dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 432 PF02746: MR_MLE_N" amino acids 33 to 136 (104 residues), 33.5 bits, see alignment E=4.2e-12 PF13378: MR_MLE_C" amino acids 202 to 415 (214 residues), 212.4 bits, see alignment E=6.7e-67

Best Hits

Swiss-Prot: 62% identical to ENOF1_BOVIN: Mitochondrial enolase superfamily member 1 (ENOSF1) from Bos taurus

KEGG orthology group: None (inferred from 93% identity to bxe:Bxe_C1347)

MetaCyc: 56% identical to L-fuconate dehydratase monomer (Xanthomonas campestris pv. campestris)
L-fuconate dehydratase. [EC: 4.2.1.68]

Predicted SEED Role

"L-fuconate dehydratase (EC 4.2.1.68)" in subsystem L-fucose utilization temp (EC 4.2.1.68)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.68

Use Curated BLAST to search for 4.2.1.68

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MAK6 at UniProt or InterPro

Protein Sequence (432 amino acids)

>H281DRAFT_00429 L-fuconate dehydratase (Paraburkholderia bryophila 376MFSha3.1)
MTTITTLSVRDIRFPTSRSLDGSDAMNAAPDYSATYVTLETDAPHALTGHGLTFTIGRGN
EICVRAVEALAPLVVGKTLEEIASDMGAFWRMLTSDSQLRWIGPDKGAIHLGTAAVVNAA
WDLWAKAEGKPVWKLLVDMSPEELVRCLDFRYVTDAITPHEAIAMLHRHAATRSERENEM
LAHGYPAYTTSAGWLGYDDDKIRRLAREGVAQGWTHFKQKVGGNLDEDMRRARILRGEIG
QDRKLMMDANQVWDVDEAIANMRHLAQFDPWWIEEPTSPDDILGHAAIRRRLAPIGVATG
EHCQNRVMFKQLLQAHAIDFCQVDSCRLGGLNEVIVVLLMAAKFGVPVCPHAGGVGLCEY
VQHISLFDYICVSASLENRVLEYVDHLHEHFVDPVVIRNGRYMPPQRPGYSIEMHAASLD
QHDFPNGPVWRP