Protein Info for H281DRAFT_00331 in Paraburkholderia bryophila 376MFSha3.1
Annotation: EAL and modified HD-GYP domain-containing signal transduction protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K07181, putative signal transduction protein containing EAL and modified HD-GYP domains (inferred from 71% identity to bgf:BC1003_3856)Predicted SEED Role
"Predicted signal transduction protein containing EAL and modified HD-GYP domains"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (424 amino acids)
>H281DRAFT_00331 EAL and modified HD-GYP domain-containing signal transduction protein (Paraburkholderia bryophila 376MFSha3.1) MSSSEQTEASQAATTRVARQPIVDRAGRLVAYELLFRDGPGPGANVHDGFGCTAEVVERT VGALGIEAVLDGLDGYLNCTADFLHSSVTQILGGRRFVLEVLETCELDNQLKKRCALLRA AGFRIALDDVLDITPDIEAFLPVVDIVKLEWPAIEAGRAKTVVRDLKRTGKVVVAEKVDD RQQLQVAIDSGCDMVQGFYFSRPELMQARRMVPDLGQVLEVLNLLIDDACDHRIIRALST MPVLVAQLLRLANCPGTANQKRTAISSLHHALAAAGTTRLFQWCSLLLYNHGDFDIVSRD PLIALATQRASLMLRLALLQRPAGTAFAQTAYLTGMLSLLHVSYAREQADFAQELPLEQS IRAALTARSGELGELLAVAESYESGPHGKARERKADACAASPLARSTIGQGMRTSPSREC FSYA