Protein Info for H281DRAFT_00222 in Paraburkholderia bryophila 376MFSha3.1

Annotation: amino acid ABC transporter membrane protein 2, PAAT family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 237 transmembrane" amino acids 20 to 47 (28 residues), see Phobius details amino acids 59 to 83 (25 residues), see Phobius details amino acids 165 to 183 (19 residues), see Phobius details amino acids 200 to 221 (22 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 21 to 122 (102 residues), 58.1 bits, see alignment E=5.2e-20 PF00528: BPD_transp_1" amino acids 39 to 228 (190 residues), 67.7 bits, see alignment E=5.9e-23

Best Hits

Swiss-Prot: 72% identical to HISM_SALTY: Histidine transport system permease protein HisM (hisM) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K10015, histidine transport system permease protein (inferred from 98% identity to bug:BC1001_0868)

Predicted SEED Role

"Histidine ABC transporter, permease protein HisM (TC 3.A.1.3.1)" in subsystem Arginine and Ornithine Degradation (TC 3.A.1.3.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5MB56 at UniProt or InterPro

Protein Sequence (237 amino acids)

>H281DRAFT_00222 amino acid ABC transporter membrane protein 2, PAAT family (Paraburkholderia bryophila 376MFSha3.1)
MIEIIQEYWRNYLYTDGYRFTGLAITLWLLVVSIGLGFCLSIPLAVARVSKKKWLSTLVW
LYTYIFRGTPLYVQLLLCYTGLYSLEIVRNHELTNAFFREGMNCTLLAFTLNTCAYTTEI
FAGAIKATPYGEIEAARAYGMSSFTLYRRVILPSALRRALPYYSNEVILMLHATTVAFTA
TVPDILKIARDVNSATYQSFNAFGIAALLYLCISFALVWLFRRAERRWLAYLRPQGK