Protein Info for H281DRAFT_00183 in Paraburkholderia bryophila 376MFSha3.1
Annotation: methionine aminopeptidase, type I
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 58% identical to MAP1_ECOL6: Methionine aminopeptidase (map) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
KEGG orthology group: K01265, methionyl aminopeptidase [EC: 3.4.11.18] (inferred from 95% identity to bgf:BC1003_0903)MetaCyc: 58% identical to methionine aminopeptidase (Escherichia coli K-12 substr. MG1655)
Methionyl aminopeptidase. [EC: 3.4.11.18]
Predicted SEED Role
"Methionine aminopeptidase (EC 3.4.11.18)" (EC 3.4.11.18)
MetaCyc Pathways
- Arg/N-end rule pathway (eukaryotic) (8/14 steps found)
- Ac/N-end rule pathway (6/21 steps found)
Isozymes
Compare fitness of predicted isozymes for: 3.4.11.18
Use Curated BLAST to search for 3.4.11.18
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A0A2Z5MB19 at UniProt or InterPro
Protein Sequence (261 amino acids)
>H281DRAFT_00183 methionine aminopeptidase, type I (Paraburkholderia bryophila 376MFSha3.1) MAITYKTPDDIAKLRISGRLAADVLAMIAEHVKAGVSTDELDALCNDYIVNTQKSIPANV GYLGFPKTVCTSVNQVVCHGIPNRSEVLKDGDIINIDVAIIKDGYFGDTSRMYCVGQPST VARQLVDTTYEAMLAGIREVKPGATLGDVGHAIQKVAQRDGFSIVRDYCGHGIGKVYHED PQVLHYGQPGQGIRLKPGMVFTIEPMINAGRAGTTVLRDGWTVVTKDRSLSAQWEHMIAV TDDGYELLTPWPDGTGSYAAP