Protein Info for H281DRAFT_00175 in Paraburkholderia bryophila 376MFSha3.1

Annotation: DNA translocase FtsK

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 771 transmembrane" amino acids 25 to 43 (19 residues), see Phobius details amino acids 73 to 93 (21 residues), see Phobius details amino acids 115 to 139 (25 residues), see Phobius details amino acids 164 to 186 (23 residues), see Phobius details PF13491: FtsK_4TM" amino acids 19 to 198 (180 residues), 169.4 bits, see alignment E=1.5e-53 PF17854: FtsK_alpha" amino acids 278 to 378 (101 residues), 104.6 bits, see alignment E=7.4e-34 PF01580: FtsK_SpoIIIE" amino acids 386 to 595 (210 residues), 240.7 bits, see alignment E=3.2e-75 PF09397: FtsK_gamma" amino acids 705 to 765 (61 residues), 90.5 bits, see alignment 1.1e-29

Best Hits

Swiss-Prot: 76% identical to FTSK2_RALSO: DNA translocase FtsK 2 (ftsK2) from Ralstonia solanacearum (strain GMI1000)

KEGG orthology group: K03466, DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family (inferred from 98% identity to bgf:BC1003_0896)

Predicted SEED Role

"Cell division protein FtsK" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton or Bacterial RNA-metabolizing Zn-dependent hydrolases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2Z5M8M3 at UniProt or InterPro

Protein Sequence (771 amino acids)

>H281DRAFT_00175 DNA translocase FtsK (Paraburkholderia bryophila 376MFSha3.1)
MAKAPYTASAQALPHRMSRLFTEIRWILQVALGVFLLMALVSYSRRDPSWTHAAQVDHIA
NWAGRVGAWTSDILLLLFGLSAYWWIVLLGRHISANYKRITRHEDLQEDAPRDASWLADA
FAFMLVLLACDGIEALRMWSLKVQLPRAPGGVIGEAVARGVSHALGFTGGTLALLIVLGI
GLSLYFRFSWLSVSEKLGESIISAVTFAKLRREAGRDRKLGEAAAVKREGKVEKGRVRIE
EHEPVVIVPPVVTPAKSERVEKERQVPLFTDLPGDSTLPPISLLDPAPAAQETISADTLE
FTSRLIEKKLKDFGVEVSVVAAYPGPVVTRYEIEPATGVKGSQIVNLAKDLARSLSLVSI
RVVETIPGKNFMALELPNQRRQTVSLSEILGSAVYADAASPLTMGLGKDIGGKPVCADLA
KMPHLLVAGTTGSGKSVGINAMILSLLYKASADQVRMILIDPKMLEMSVYEGIPHLLCPV
VTDMRQAGHALNWAVAEMERRYKLMSKLGVRNLAGYNNKIDEAAKREEKLPNPFSLTPDE
PEPLTRLPNIVIVIDELADLMMVVGKKVEELIARIAQKARAAGIHLILATQRPSVDVITG
LIKANVPTRMAFQVSSKIDSRTILDQQGAESLLGMGDMLYLPPGSGLPVRVHGAFVSDEE
VHRVVDKLKEQGEPNYIEGILEGSVTGEGDEGSAGAGAGGSGDGESDPLYDQAVDVVLKN
KRASISLVQRHLRIGYNRAARLLEQMENSGVVSAMSSNGNREILAPAREAE