Protein Info for H281DRAFT_00114 in Paraburkholderia bryophila 376MFSha3.1

Annotation: sulfite reductase (NADPH) beta subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 50 to 110 (61 residues), 55.6 bits, E=3.6e-19
  • amino acids 332 to 398 (67 residues), 47.9 bits, E=9e-17
• PF01077: NIR_SIR
  • amino acids 119 to 273 (155 residues), 157.5 bits, E=1.9e-50
  • amino acids 411 to 550 (140 residues), 52.1 bits, E=5.4e-18

Best Hits

KEGG orthology group: K00381, sulfite reductase (NADPH) hemoprotein beta-component [EC: 1.8.1.2] (inferred from 97% identity to bug:BC1001_0729)

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• superpathway of L-methionine biosynthesis (by sulfhydrylation) (11/12 steps found)
• assimilatory sulfate reduction I (4/4 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (7/10 steps found)

KEGG Metabolic Maps

• Sulfur metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.8.1.2

Sequence Analysis Tools

See A0A2Z5M8H6 at UniProt or InterPro

Protein Sequence (559 amino acids)

>H281DRAFT_00114 sulfite reductase (NADPH) beta subunit (Paraburkholderia bryophila 376MFSha3.1)
MYQYDQYDQTIVDERVAQYADQVRRRLSGELSEEEFRPLRLQNGLYYQRHAYMHRIAIPY
GNLRSDQLRMLAQIAREHDRGYGHFSTRSNIQYNWIKLEETPEILRKLASVQMHGIQTSG
NCIRNITADQFAGVAPDEFVDPRPWAEILRQWSTFHPEFAWLPRKFKIAVSGSHEDRAAV
QIHDMGVYVKRNAQGELVVDILAGGGLGRTPIVGAVIRKDLPWQHLLTYSEAVLRVYNRY
GRRDNMYKARIKILVKALSPEKFAAQVEEEWQHLKDGPSTLTQAELDRVSQYFQPPVYEK
LADTDASFEKHLLENRAFARWVERNVRPHKVSGYAAVTLSLKNGVVAPGDATDAQMEAVA
DWADEYSLGEIRVSHEQNLILANVKKRDLFALWEKAKAQGFATPNIGLLTDIIACPGGDF
CSLANAKSIPIALAIQERFNDLDYVYDLGDVSLNISGCINACGHHHVGNIGILGVDKDGS
EWYQVTLGGEQGTGASGAQLGRVIGPSFSAEEMPDVMTKVIDTFVENRHEGERFIDTYTR
IGMAPFKERVYASRQPAHA