Protein Info for Ga0059261_3725 in Sphingomonas koreensis DSMZ 15582

Annotation: translation elongation factor EF-G

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 697 TIGR00484: translation elongation factor G" amino acids 1 to 695 (695 residues), 1090.1 bits, see alignment E=0 TIGR00231: small GTP-binding protein domain" amino acids 9 to 188 (180 residues), 102.6 bits, see alignment E=2e-33 PF00009: GTP_EFTU" amino acids 9 to 288 (280 residues), 215 bits, see alignment E=1.8e-67 PF03144: GTP_EFTU_D2" amino acids 330 to 396 (67 residues), 64.7 bits, see alignment E=2.1e-21 PF14492: EFG_III" amino acids 409 to 482 (74 residues), 115.5 bits, see alignment E=2.3e-37 PF03764: EFG_IV" amino acids 484 to 602 (119 residues), 146.1 bits, see alignment E=1.1e-46 PF00679: EFG_C" amino acids 605 to 691 (87 residues), 108.7 bits, see alignment E=3e-35

Best Hits

Swiss-Prot: 89% identical to EFG_SPHWW: Elongation factor G (fusA) from Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273)

KEGG orthology group: K02355, elongation factor G (inferred from 89% identity to swi:Swit_1356)

Predicted SEED Role

"Translation elongation factor G" in subsystem Translation elongation factor G family or Universal GTPases

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6JE10 at UniProt or InterPro

Protein Sequence (697 amino acids)

>Ga0059261_3725 translation elongation factor EF-G (Sphingomonas koreensis DSMZ 15582)
MARSHPLERYRNIGIMAHIDAGKTTTTERILYYTGKSYKIGEVHEGTATMDWMEQEQERG
ITITSAATTCKWRAAEGKGEEHLINIIDTPGHVDFTIEVERSLRVLDGAVTCFDGVAGVE
PQSETVWRQADKYRVPRLCYVNKLDRTGASFERCVNMIKDRLGARTAVLYLPIGIESQFV
GLVDLVENRAIVWLDESLGAKFEYRDIPDDMKDAAAAARGELIEIAVEQDDAAMDAYLEG
NEPDIPTLKALIRKGTLAFDFVPVLCGSSFKNKGVQPLLDAVVDYLPSPLDIPDVQGVKL
DGETPDSRPPADDAPMSLLAFKIMNDPFVGSLTFARIYSGTLSKGQYLNSVKDKKEKIGR
MLLMHANSREDIDEARAGDIVAIAGLKETTTGDTLCDSAHPIILERMEFPEPVIELSVEP
KTKADQEKMGIALNRLAAEDPSFRVSTDHESGQTIIKGMGELHLEILVDRMKREFKVEAN
VGAPQVAYREYLAKPVDIDYTHKKQSGGTGQFGRVKVKLTPGERGSGFVFKDEIKGGNIP
KEYIPAIEKGFRETAETGSLVGFPIIDFEVLLYDGAYHDVDSSALAFEITARGAMREAAQ
KSGIKLLEPIMKVEVVTPEDYLGDVIGDINSRRGQIQGTDSRGNAQTVEAMVPLANMFGY
VNQLRSFTQGRAQYSMQFSHYDEVPPNVADEVKAKLA