Protein Info for Ga0059261_3540 in Sphingomonas koreensis DSMZ 15582

Annotation: Reverse transcriptase (RNA-dependent DNA polymerase)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 690 transmembrane" amino acids 460 to 478 (19 residues), see Phobius details PF00078: RVT_1" amino acids 194 to 361 (168 residues), 48.6 bits, see alignment E=4.3e-17

Best Hits

KEGG orthology group: None (inferred from 85% identity to bps:BPSL0582)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WH10 at UniProt or InterPro

Protein Sequence (690 amino acids)

>Ga0059261_3540 Reverse transcriptase (RNA-dependent DNA polymerase) (Sphingomonas koreensis DSMZ 15582)
MAKRRVSLTHRKQRSVLTDMLPFEVPPTFSNRGYYRFLRNNSIEIEKGQLRWICETDALD
RTMRLLFGIDLAANITPEVVTEWGKQKTRRSVPLKKCKMATMPFNFRVAHNLDGRTLSVV
HPRNQVEVASFYATHSALIIYHTSVSEFSIRRPVSVSRYAYFKDKLHEERLDSVAGLEEE
DREYEQLGSYFVYRKYRNIHRFFESYKYHRSEKKYDAMVQIDVSKCFDSIYTHSLPWAVL
GKDQTKFSLDASKGTFGGRFDALMQNLNHKETNGIVIGPEFSRIFAEIILQSVDSELIRQ
LAEGANLTHKIDYEIFRYVDDFFVFYNEESTQLKIFETLQDILKGKKLSINTAKIKHYQK
PIITEITIGKERISALLNAEIDPACEEEPLADPTKTPKQKLVCSINANRLIIRYKAAIKE
AGVTYGDLLNYTFAITENKIEKLFKAYVASDKSDRDRKRLSNALLAIMEFAFFAYSASPK
VNHTIRLCRMIATSVDFLHAQGLPYEQKHLLFKYVHDNVMQQLEKNTMSVHREVESLYLL
IALPQIGREYWLPVSVLLRHFLIKEEENTGNYIRPTGFMNHFSVTILLSYIKDKVRYAKL
KTFIEAHIIAKLEYMKAHCPDDAETLIMLLDLVVCPYISAATKDAIGLIFKLDAAGLASV
QAANDHWFTAWGDKFDLGKELDAKRSREVY