Protein Info for Ga0059261_2879 in Sphingomonas koreensis DSMZ 15582

Annotation: Glycerol dehydrogenase and related enzymes

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 358 PF00465: Fe-ADH" amino acids 8 to 323 (316 residues), 152.1 bits, see alignment E=2e-48 PF13685: Fe-ADH_2" amino acids 14 to 272 (259 residues), 96.5 bits, see alignment E=2.2e-31

Best Hits

KEGG orthology group: K00005, glycerol dehydrogenase [EC: 1.1.1.6] (inferred from 49% identity to mno:Mnod_5662)

Predicted SEED Role

"Glycerol dehydrogenase (EC 1.1.1.6)" in subsystem Respiratory dehydrogenases 1 (EC 1.1.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WF61 at UniProt or InterPro

Protein Sequence (358 amino acids)

>Ga0059261_2879 Glycerol dehydrogenase and related enzymes (Sphingomonas koreensis DSMZ 15582)
MIRIFGGPTRYVQGPGAIGELGTLTERLTKRPLLVVDADVLPFVEAQLSTAFAGRPSITL
AFRGEVTHAAIDLLVEQAGDADCVIGIGGGKGLDAAKGVAFKLGLPFIAVPSIASNDSPT
GRSMAIYNDEHVLVAIETIPDSPLLVVTDTQLIANAPARFLRTGMGDALAKKFEAERAVA
DGASNFFGTRQLRTALAIADACYQTLREHGVAAMAAAERHEPDEAFEAVVEANVLMAGLA
WESGGLSYAHAVVRGLVKARGAASAPHGDHVGYATLVQLAIEGRDDGFILDVIGFNRSVG
LPASLAELDMGSPTPDEIAEIARLTTIGPKGGRIIVNAGPGQIADAIKRVEQLATRES