Protein Info for Ga0059261_2601 in Sphingomonas koreensis DSMZ 15582

Annotation: DNA-methyltransferase (dcm)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00675: DNA (cytosine-5-)-methyltransferase
  • amino acids 18 to 346 (329 residues), 108.3 bits, E=3.2e-35
• PF00145: DNA_methylase
  • amino acids 18 to 348 (331 residues), 163.1 bits, E=5.8e-52

Best Hits

KEGG orthology group: K00558, DNA (cytosine-5-)-methyltransferase [EC: 2.1.1.37] (inferred from 73% identity to sch:Sphch_2001)

Predicted SEED Role

"DNA-cytosine methyltransferase (EC 2.1.1.37)" (EC 2.1.1.37)

KEGG Metabolic Maps

• Methionine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.37

Sequence Analysis Tools

See A0A2M8WEE6 at UniProt or InterPro

Protein Sequence (368 amino acids)

>Ga0059261_2601 DNA-methyltransferase (dcm) (Sphingomonas koreensis DSMZ 15582)
MNGETALHIEANGRSTAVVDLFCGAGGLAYGLQAAGLTVKAGVDLDPSCRYPIEKNTGAE
FALKDISELKPAELRRWFGDAQVRVLAGCAPCQPFSTYSQSRKSVDRRWTLLKQFQRLAL
AVKPEIVTMENVPGLATQAVWKRFTAALEKAKYHVSWREVSCDEFGVPQSRRRLVLLASL
LGPIELRPVEGVLKLTVRDVIENLPPIEAGSSAPIDRLHASASLTARNLERIRASRPGGT
WRDWPEDLRAPCHRKITGKTYPSVYGRMEWDKPAPTMTTQCYGFGNGRFGHPEQDRAISL
REAAILQSFPREYSFLGEEDDVTFERLGTLIGNAVPPKLGEAIGRSILAHIDALDNDRPT
LEGQLDLR