Protein Info for Ga0059261_2514 in Sphingomonas koreensis DSMZ 15582

Annotation: phosphoenolpyruvate-protein phosphotransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 759 PF01590: GAF" amino acids 30 to 157 (128 residues), 58.8 bits, see alignment E=2.7e-19 PF13492: GAF_3" amino acids 30 to 162 (133 residues), 38.1 bits, see alignment E=5.9e-13 PF13185: GAF_2" amino acids 31 to 160 (130 residues), 52.2 bits, see alignment E=2.4e-17 PF05524: PEP-utilisers_N" amino acids 187 to 305 (119 residues), 77.9 bits, see alignment E=2.2e-25 TIGR01417: phosphoenolpyruvate-protein phosphotransferase" amino acids 187 to 725 (539 residues), 381.5 bits, see alignment E=3.1e-118 PF00391: PEP-utilizers" amino acids 333 to 403 (71 residues), 57.5 bits, see alignment E=2.7e-19 PF02896: PEP-utilizers_C" amino acids 434 to 724 (291 residues), 292.5 bits, see alignment E=9.6e-91

Best Hits

KEGG orthology group: K08484, phosphotransferase system, enzyme I, PtsP [EC: 2.7.3.9] (inferred from 76% identity to swi:Swit_4505)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.9

Use Curated BLAST to search for 2.7.3.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WE61 at UniProt or InterPro

Protein Sequence (759 amino acids)

>Ga0059261_2514 phosphoenolpyruvate-protein phosphotransferase (Sphingomonas koreensis DSMZ 15582)
MPVSAAASAREILTRLHDVMASRAAAQGKLNSVVNIIGEALNSEVCSIYLLREGALELFA
TRGLAQEAVHVTKLAMGEGLTGTIAANVETLNLDEAAAHPDFAYRPETGEDRFHSYAGVP
IIRKERAVGVLAVQHADPRKYDEVEIEALQTVAMVLSELIANAGLIDPAGGGGTTRLQST
GTARVPGFKLVEGMAAGAAVFHQPRIIIEHTVAEDIEAERHRVYAAFDKMREQIDRMTSQ
AEFGGGGEHEEVLETYKMFAYDEGWSRRINEAIDSGLTAEAAIERVQQRTRMRMRQIDDP
LLRDRMHDLEDLSNRLLRIVSGQLGTAAQLGLRQDSILIARNLGPAELLEYDRRRLKGVV
LEEGSLTAHVTIVARAMGVPVLGRVKDIRRLIAEGDRLLVDVTEDTLIIRPTAAMDEAFE
AKLLVTQKRRAAFAALKNEAPVTTDGHRLTVMVNAGLRDDVAALDLTGADGIGLFRTEFQ
FLVSATLPQRDSQRRLYKDVLDAAGDRPVTFRTVDIGGDKALPYLDHDENGEEENPAMGW
RALRLALDREGLMKVQARALLEAAAGRTLNVMFPMVSEPWEFDEARTLFETQRAWLESRG
HKLPLHIRYGAMLEVPALAEVLDLLLPRLDFLSVGTNDLTQFLFAADRAHPKLAVRYDWL
SPSILRFLRRVTAEAAEADVPLAVCGEMGGRPLEAMALIGLGIDRLSITPAAVGPIKAMV
RSLDRAKLIAAMRGMLDRPPQDMRAALEQWAADHGVELA