Protein Info for Ga0059261_2476 in Sphingomonas koreensis DSMZ 15582

Annotation: DNA-directed DNA polymerase III (polc)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1118 PF02811: PHP" amino acids 11 to 136 (126 residues), 35.3 bits, see alignment E=3.9e-12 TIGR00594: DNA polymerase III, alpha subunit" amino acids 148 to 1014 (867 residues), 494.8 bits, see alignment E=2.9e-152 PF07733: DNA_pol3_alpha" amino acids 287 to 540 (254 residues), 276.3 bits, see alignment E=7.5e-86 PF17657: DNA_pol3_finger" amino acids 543 to 711 (169 residues), 176.9 bits, see alignment E=5.6e-56 PF14579: HHH_6" amino acids 784 to 891 (108 residues), 70.2 bits, see alignment E=3.6e-23 PF01336: tRNA_anti-codon" amino acids 979 to 1054 (76 residues), 35.6 bits, see alignment 1.9e-12

Best Hits

Predicted SEED Role

"DNA polymerase III alpha subunit (EC 2.7.7.7)" in subsystem DNA-replication (EC 2.7.7.7)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WE07 at UniProt or InterPro

Protein Sequence (1118 amino acids)

>Ga0059261_2476 DNA-directed DNA polymerase III (polc) (Sphingomonas koreensis DSMZ 15582)
MSPTPANYAELQVTTHYSFLRGASAPQDLFRQAALLGLPALGIVDRNSVGGVVRALVAAE
ELAAHGIPIRMIAGCRLDLTDGSSVLVWPEDRAAWSRLTRLLTLGKGRADAQKGEKGRCF
LHWEDVANAAEGLVGALVPGIADPGDPQALRWMADTFGERGHVCLTQHRRPGDALRLYRL
DETARRFGLTPLATGDVLYATPGERMLQDVVTAIRERCTIDELGFRRERSADRHLKSPGD
MARRFRDHPEALRASLAIAERCTFSLRDLQHQYPEEQVIPGRTAQEALSTLAWNGLRQRF
GGNPSQAHQDLLVHELGLVERMGYAPYFLTVNSIVQFALSQQILCQGRGSAANSVICFAL
GITSIDPIEHQLLFERFISTERREPPDIDVDFEHERREEVIQWIYEYYGHDHAALTAVVS
RFRSRGALREVGKALGLPEDLTAALSSQVWGWSNDVDDKHADALNLDRNDPRLALTLALA
RQLIGTPRHLSQHPGGFVLTRDKLHDLIPVEPAAMIDRRVVEWEKLDIEELGFMKVDILG
LGMLGCMRRTFDLLAKYKGIHLTLASPLMQKDDGPTFEMIRQADTLGVFQIESRAQMSML
PRMKPVNFYDIAIQVAIVRPGPIQGNMVHPYLKRRQNPDLVDYPTPKLKAVLEKTLGVPL
FQEQAMQVAIVGADFTPTEADRLRRAMATFKSSGDIGEFAPKLIAGMRRNGISQEFAERM
VEQIKGFSNYGFPESHAASFAKIAYASSWMKCHHPDVFCTALLNAQPMGFYAPAQLIRDA
RAHGVEVRPVCINDSDWDTRVIPEGPNARERDGRFCGTDEDWSGIQPIRLGMRIVQGLAL
GDVTEILRARRQASFTSIEDVWRRSGVKPAALERLARADAFQALGLNRRQALWAIKGLGQ
KPLDLFTAADARAGQTVAESVEPSVALVPLTAGREVVEDYRATQLSLRAHPLSFLRDRLV
AQGITKCADLIRMKDGARVEIAGLILVRQRPGTASGIVFVTLEDETGIANVVLWSDRFEA
NRRTVMSATMLSIRGRVQREGIVIHVIADTITDLTGMLREVGDLDLPHTAMPGDGATHGG
TIDPRDRLISRQRPADSWPPRRSLKTPDLIPVKSRDFH