Protein Info for Ga0059261_2176 in Sphingomonas koreensis DSMZ 15582

Annotation: AAA family ATPase, CDC48 subfamily

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 763 TIGR01243: AAA family ATPase, CDC48 subfamily" amino acids 9 to 707 (699 residues), 918.5 bits, see alignment E=4.6e-280 PF02359: CDC48_N" amino acids 10 to 91 (82 residues), 72.9 bits, see alignment E=2.5e-23 PF02933: CDC48_2" amino acids 115 to 190 (76 residues), 44.6 bits, see alignment E=1.1e-14 PF07728: AAA_5" amino acids 239 to 358 (120 residues), 27.3 bits, see alignment E=4.1e-09 PF00004: AAA" amino acids 240 to 369 (130 residues), 154.2 bits, see alignment E=3.1e-48 amino acids 514 to 644 (131 residues), 150.1 bits, see alignment E=6e-47 PF17862: AAA_lid_3" amino acids 393 to 431 (39 residues), 47.6 bits, see alignment 1.2e-15 amino acids 667 to 713 (47 residues), 52.4 bits, see alignment 3.7e-17

Best Hits

KEGG orthology group: K13525, transitional endoplasmic reticulum ATPase (inferred from 80% identity to sch:Sphch_2014)

Predicted SEED Role

"Cell division protein FtsH (EC 3.4.24.-)" in subsystem Bacterial Cell Division (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6J6Y0 at UniProt or InterPro

Protein Sequence (763 amino acids)

>Ga0059261_2176 AAA family ATPase, CDC48 subfamily (Sphingomonas koreensis DSMZ 15582)
MAETDTPTRKLQVANSRPEDSGRGLAHLPRTLMGELGLQQGDVIEIVGKRITPARAVFPY
PEDEGLELLRIDGLQRANAGVGSGDFVEIRRGESRPATRVVFAPARKDLRLEGSANALKR
TFIGRPLAQGDTVSTVGQQRVADMPPNVLQHLRAPAYALQEIRLTVVSAAPRGIVHIDES
TEIELRTDYEEAKEFRRADVTYDDIGGMAATIDQLREMVELPLRYPELFQRLGVDPPKGV
LLHGPPGTGKTRLARAVANESDASFFLINGPEIMGSAYGESEKRLREVFEEANANSPAII
FIDEVDSIAPKRGQVTGEAEKRLVAQLLTLMDGLEARANVVIIAATNRPEALDEALRRPG
RFDREIVVGVPDERGRREILGIHTRGMPLGDKVDLTELARTTFGFVGADIAALTREAAIE
AVRRIMPKLNLEEKTIPPEVLETLAVTREDFVEALKRVQPSAMREVMVQKPNVHWEDVGG
LDDAQMRLKEGVELPMKDPDAFRRLGIRPAKGFLLYGPPGTGKTLLAKAVAREAEANFIA
TKSSDLLSKWYGESEQQIARLFARARQVAPCVIFIDELDSLVPARGSGMGEPQVTERVVN
TILAEMDGLEELQSVVVIGATNRPNLIDPALMRPGRLDELIYVGVPDAAGRERILKIQTA
KMPLADDVDLGSIAERTERFTGADLEDVVRRAGLVALRESLTNTHVTMAHFEAALADSRA
TVTPEMEAEYAQLVARMKQDAVALNPIGFIAPGMLQSRKKDAG