Protein Info for Ga0059261_2149 in Sphingomonas koreensis DSMZ 15582

Annotation: NusA antitermination factor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 543 PF08529: NusA_N" amino acids 11 to 131 (121 residues), 117.1 bits, see alignment E=1.6e-37 TIGR01953: transcription termination factor NusA" amino acids 11 to 348 (338 residues), 416.3 bits, see alignment E=8.5e-129 PF00575: S1" amino acids 138 to 200 (63 residues), 28.8 bits, see alignment E=3.9e-10 PF13184: KH_5" amino acids 236 to 303 (68 residues), 96.2 bits, see alignment E=2.9e-31 PF07650: KH_2" amino acids 292 to 345 (54 residues), 23.4 bits, see alignment 1.3e-08 PF14520: HHH_5" amino acids 371 to 416 (46 residues), 20 bits, see alignment 2.4e-07 TIGR01954: transcription termination factor NusA, C-terminal duplication" amino acids 371 to 420 (50 residues), 63.3 bits, see alignment 1.7e-21

Best Hits

Swiss-Prot: 42% identical to NUSA_HAEIN: Transcription termination/antitermination protein NusA (nusA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02600, N utilization substance protein A (inferred from 86% identity to swi:Swit_3819)

Predicted SEED Role

"Transcription termination protein NusA" in subsystem NusA-TFII Cluster or Transcription factors bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6J6N4 at UniProt or InterPro

Protein Sequence (543 amino acids)

>Ga0059261_2149 NusA antitermination factor (Sphingomonas koreensis DSMZ 15582)
MATAISANKAELIAIANSVASEKMIDKSIVIEAMEEAIERAAKNRYGVENDIRAKLDPQT
GDLRLWRVVEVVEAVDDYFKQVDLKGAQKLQKDAKVGDFIVDPLPPIEFGRIQAQASKQI
IFQKVRDAERERQFEEFKDRQGEIITGVVKRVEFGHVVVDLGRAEGVIRRDAQIPREVVR
VGDRVRSLILKVVRETRGPQIFLSRAHPDFMKKLFAQEVPEIYDGIIEIKAAARDPGSRA
KIGVISHDSSIDPVGACVGMKGSRVQAVVQEMQGEKIDIIPWSPDTATFVVNALQPANVA
RVVIDEEDDRIEVVVPDDQLSLAIGRRGQNVRLASQLTGKAIDILTETDSSEKRQAEFVA
NSEMFQNELDVDETLAQLLVAEGFSQLEEVAYVELDELAGIEGFDEDLAQELQSRAAEAL
ERREEANRTARRELGVEDDLATMPYLTEAMLVTLGKAGIKTLDDLADLATDELVAKKRPE
PRRRGDGPAAPVRESDKGGVLGEYGLSDEQGNEIIMAARAHWFADEEESAPAGGEDAVAD
SEQ