Protein Info for Ga0059261_1846 in Sphingomonas koreensis DSMZ 15582

Annotation: Xaa-Pro aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 PF01321: Creatinase_N" amino acids 7 to 138 (132 residues), 55.2 bits, see alignment E=2.1e-18 PF16189: Creatinase_N_2" amino acids 148 to 306 (159 residues), 142.1 bits, see alignment E=3.4e-45 PF00557: Peptidase_M24" amino acids 310 to 527 (218 residues), 180 bits, see alignment E=1.1e-56 PF16188: Peptidase_M24_C" amino acids 537 to 597 (61 residues), 83.7 bits, see alignment 1.4e-27

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 70% identity to sjp:SJA_C1-01520)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WCC1 at UniProt or InterPro

Protein Sequence (600 amino acids)

>Ga0059261_1846 Xaa-Pro aminopeptidase (Sphingomonas koreensis DSMZ 15582)
MSTYADRLNALRAQLKREQLDGFVVPLTDEHMSEYVGGYAQRLGWLTGFQGSAGSAVVLP
EAAAIFTDGRYTLQVRQQVDGNHWEYVPVPQVSIASWLGEHAPQGGRIGYDPWLHTRGWV
EEARKALAEKGAELVAVERNPIDAVWDDRPLPSDAKLSVQSDDAAGQTSAAKRAGIADWL
AERKADAVVLSALDSIAWAFNVRGTDVSHTPVALAYAIVNSDGTADLFVAKDKVGEDVAK
HLGNAVRVHDRSAFAPALQQFAGKRVAADPAGSVAAIFDALDAGGAKILAVRDPVVLAKA
IKNEAEISGHRAAQARDGAALARFLKWAEAEMPKGGVTEISAANRLQAFREETGLLKDLS
FDTISATGPNGAIPHYKVTEESSLPVENGQLYLVDSGGQYEDGTTDVTRVIPVGEPTQEM
RDRFTRVLKGHIAIATAVFPAGTTGGQIDSFARRPLWEVGCDYGHGTGHGVGAYLSVHEG
PQRIAAPNYPGGGPAEPLRAGMFLSNEPGYYKAGEFGIRIENLVLVIEKDIPGAESPMLG
FETLTFAPIERDLIEPALLTEDERRWLDAYHAKVLEVLGPQLSPDERVWLEAKCRPITAR