Protein Info for Ga0059261_1624 in Sphingomonas koreensis DSMZ 15582

Annotation: 2-keto-3-deoxy-galactonokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

KEGG orthology group: K00883, 2-dehydro-3-deoxygalactonokinase [EC: 2.7.1.58] (inferred from 49% identity to sal:Sala_0743)

Predicted SEED Role

"2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58)" in subsystem D-galactonate catabolism (EC 2.7.1.58)

MetaCyc Pathways

D-galactonate degradation (2/3 steps found)
L-glucose degradation (3/7 steps found)

KEGG Metabolic Maps

Galactose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.58

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WBN6 at UniProt or InterPro

Protein Sequence (292 amino acids)

>Ga0059261_1624 2-keto-3-deoxy-galactonokinase (Sphingomonas koreensis DSMZ 15582)
MVVRPREPLLAVDWGTTNRRVYLLEDGAVARTERDDRGVTAVRDFASEAADIRARFGDLP
MLIAGMVGSNIGWRTAPYVPAPAGVGELAANLLKIDERTAIVPGVSTLAHQRPDVMRGEE
VQLLGAVAAGLAPGDALLVQPGTHCKWAQMRGGRITGFTTAMTGELFALLRSHGLLAAQL
TGEVSANTAFRQGVEEAKRRDLAASLFGIRAAKILGTRDDADAAAYASGLLIGSDVAARI
DQAPDAEMFILSGPELGNLYIAAIEMHDRAASLIDSQTAFVAGILAIGNVFQ