Protein Info for Ga0059261_1569 in Sphingomonas koreensis DSMZ 15582

Annotation: Response regulator receiver domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 125 PF00072: Response_reg" amino acids 4 to 112 (109 residues), 80.7 bits, see alignment E=4.5e-27

Best Hits

Swiss-Prot: 60% identical to CPDR_BRUA2: Response regulator receiver protein CpdR (cpdR) from Brucella abortus (strain 2308)

KEGG orthology group: K13589, two-component system, cell cycle response regulator CpdR (inferred from 83% identity to swi:Swit_0135)

Predicted SEED Role

"Response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6J8T1 at UniProt or InterPro

Protein Sequence (125 amino acids)

>Ga0059261_1569 Response regulator receiver domain (Sphingomonas koreensis DSMZ 15582)
MIRILLAEDDRVMREYLARALERSGYAVTAVDRGTAALPLIEAERFDLLLSDIVMPEMDG
IELAQKAGEIAPDMRVMFITGFAAVTLKAGKQIPSARVLSKPFHLRDLVLEVDRLFEMEQ
VPSRN