Protein Info for Ga0059261_1465 in Sphingomonas koreensis DSMZ 15582

Annotation: Predicted Zn-dependent peptidases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 970 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF00675: Peptidase_M16" amino acids 79 to 191 (113 residues), 67.3 bits, see alignment E=1.4e-22 PF05193: Peptidase_M16_C" amino acids 230 to 407 (178 residues), 49.5 bits, see alignment E=5e-17 amino acids 711 to 835 (125 residues), 26.7 bits, see alignment E=4.8e-10

Best Hits

KEGG orthology group: K07263, zinc protease [EC: 3.4.24.-] (inferred from 49% identity to sjp:SJA_C1-20470)

Predicted SEED Role

"peptidase M16-like protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8WB86 at UniProt or InterPro

Protein Sequence (970 amino acids)

>Ga0059261_1465 Predicted Zn-dependent peptidases (Sphingomonas koreensis DSMZ 15582)
MALFPRVKQLALPLLVAAAAIPAIAQVAAPAPVAAPVAVDKAPWLYKGSDVPHDPEWRFG
TLPNGLRYAVRKNGVPPGQVSIRLRMDVGSLMERESEKGFAHLLEHLSFRGSAKVPDGES
KREWQRLGVTFGSDSNASTTPVSTTYKLDLPDANETSLDKSMMILADMMAAPNITTAMLN
LERPVVLAEQRERLRPQQRFEDAQRELFYAGQLFAERPVIGTVETLNGATADSVRAFHQR
WYRPERATLVIVGDLDPALFETQIAKHFAAWRGTGPNPVTPDFGKPDPAKPTSAALVEPT
LPPYVTLAVLRPWTVFQDTVKFNQERMIDFIALRIINRRLESRARAGANFAGAGADLSDD
VRSANVTAIQVLPLGEDWESAVKEVRAVIADALATAPTQAEIDREVAEIDSGMRNSVSTA
PVMAGSRRADNLVEAVDINEVTTSEQESYNIFKGAVDGRMFTPDRVLASTRRILQGDATR
AVINTRTADPDVQAKLAAVLKADVSGLAGTRSTARNVTFASLPALGAPGKVAERTIAVAD
PKIETVRFANGVNLILFQNPGEVGRVYVNVRFGRGMQGIPSGRQTPAWAGGMALVASGIS
APGGTLGQEELDKLTGDRQIGLSFGIGDDAFTFAGQTRKEDLEDQLKLIAAKLQSPGWDP
KPVARARAVSISGYASSSSSPDAVIGRDLERLLHDNDPRWGMPDLKGIEALNAKDFRAFW
APLLASGPIEVQIFGDIDVEKAVEAARVTFGAMKPRKATPPVAAAMRFPQNVVKPVQLTH
SGQPDQAAAVIAWQAGGGSDNIAEGRKLEILAAVMRDRILDRIRSAEGASYSPTVISQWP
VGQPGGGRIMAITLIPPDKTDLFFRVSREIAADLIARPIDTDELRRALVPTAQMVVRRSS
GNPFWMQQTEGGTFDPKRFAAIGSIARDYGATTPQELQMLAAKYLAPQKDWSMVVVPETK
PAAATAAGGR