Protein Info for Ga0059261_0981 in Sphingomonas koreensis DSMZ 15582

Annotation: Alpha/beta hydrolase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 transmembrane" amino acids 148 to 165 (18 residues), see Phobius details PF12697: Abhydrolase_6" amino acids 97 to 326 (230 residues), 30.5 bits, see alignment E=2.9e-11

Best Hits

KEGG orthology group: K03821, polyhydroxyalkanoate synthase [EC: 2.3.1.-] (inferred from 50% identity to sjp:SJA_C1-16970)

Predicted SEED Role

"Polyhydroxyalkanoic acid synthase" in subsystem Polyhydroxybutyrate metabolism

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.-

Use Curated BLAST to search for 2.3.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8W9X6 at UniProt or InterPro

Protein Sequence (350 amino acids)

>Ga0059261_0981 Alpha/beta hydrolase family (Sphingomonas koreensis DSMZ 15582)
MVLTPFDTAPQHGPRPLPLFLGLLRSETAASPERRAAALAGLAAYQAARRPRPRSSMPVV
ARAGRAVLRDYGGSGAPVVFVPSLINPPLILDMPYRRSLLRWLSRHGARPLLIDWGTPSP
QDRAQDVAQHVEAMLIPLLRSIGEPAALVGYCLGGTMAMAAAAVAPVRGLALIAAPWRFS
GFGAEAIARIETLWDGARETCDRLGLVPMEVLQTGFWQLDPARTIIKYERFGRLDPDSAA
AKSFVAMEDWANAGAPLTFAAGRQIFDDLFTADLPGSGRWRVAGATAAPASLPCPTVEFV
SLTDRIVPHTSAAGFTDRRELRLGHVGMMVGSSAKDALWRPLAEWLAALR