Protein Info for Ga0059261_0975 in Sphingomonas koreensis DSMZ 15582

Annotation: Flp pilus assembly protein, ATPase CpaF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 489 PF00437: T2SSE" amino acids 144 to 416 (273 residues), 221.6 bits, see alignment E=1.1e-69

Best Hits

KEGG orthology group: K02283, pilus assembly protein CpaF (inferred from 87% identity to sjp:SJA_C1-26870)

Predicted SEED Role

"Type II/IV secretion system ATP hydrolase TadA/VirB11/CpaF, TadA subfamily" in subsystem Widespread colonization island

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6J9U6 at UniProt or InterPro

Protein Sequence (489 amino acids)

>Ga0059261_0975 Flp pilus assembly protein, ATPase CpaF (Sphingomonas koreensis DSMZ 15582)
MQGGGAAPRPQEPLGGDQFPAIQDVPLPGANQRDSGITDTTPQSTTDAMQRLADRQAASG
EAGSSRVEGFEASIHRIKEQVLPRLLERVDPEAAATLNKDELAEEFRPIIGEVLAELKLT
LNRREQFALEKVLVDELLGLGPLEELLADSAISDIMVNGPEQTFVERKGKLELANINFRD
EEHLFQIAQRICNSVGRRVDQTTPLADARLKDGSRVNVIVPPLSLKGTAISIRKFSDKPI
TLDMMAGFGSMSTKMATALKIAGACRFNIVISGGTGSGKTTMLNALSKMIDPGERVLTIE
DAAELRLQQPHWLPLETRPPNLEGQGEITIRDLVKNALRMRPDRIILGEIRGSECFDLLS
AMNTGHDGSMCTLHSNSPRECLGRMENMVMMGDIKIPKEAISRQIADSVDLIVQVKRLRD
GSRRVTNITEVIGMEGPVIVTQELFKFEYLDESADGKIIGEYRSMGLRPYTLEKARSFGF
DHALLEACL