Protein Info for Ga0059261_0958 in Sphingomonas koreensis DSMZ 15582

Annotation: ATP-dependent DNA helicase RecG (EC 3.6.1.-)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 685 PF04851: ResIII" amino acids 260 to 415 (156 residues), 36.7 bits, see alignment E=8.1e-13 PF00270: DEAD" amino acids 260 to 421 (162 residues), 80.8 bits, see alignment E=2.1e-26 PF00271: Helicase_C" amino acids 460 to 572 (113 residues), 66.7 bits, see alignment E=4.4e-22 PF19833: RecG_dom3_C" amino acids 599 to 656 (58 residues), 34.3 bits, see alignment 4.1e-12

Best Hits

KEGG orthology group: K03655, ATP-dependent DNA helicase RecG [EC: 3.6.4.12] (inferred from 74% identity to swi:Swit_1516)

Predicted SEED Role

"ATP-dependent DNA helicase RecG (EC 3.6.1.-)" in subsystem DNA-replication (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-, 3.6.4.12

Use Curated BLAST to search for 3.6.1.- or 3.6.4.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8W9V4 at UniProt or InterPro

Protein Sequence (685 amino acids)

>Ga0059261_0958 ATP-dependent DNA helicase RecG (EC 3.6.1.-) (Sphingomonas koreensis DSMZ 15582)
MRPDILNPLFAEVTALKGVGPQLAKPLERLGLARVVDVAFHLPSGWIDRLPREELDAADV
GRIIAITLTPVNYRMGGSARAPSRVEAVDAKGNYVTLVFFGGNSGWAKKQLPLNEPRWVS
GKLDQYGQELQIVHPEVVAPEAAEPTGREAIYPLSEGMTSKRLAALAAQAIERAPELPEW
IEPSLKDRNGWPAWREALARIHADPADAKARDRLAYDEVFANQLALMLVRGAARAKKGRP
LAGDGRLRDALHLPYTPTGAQARTIREIEGDMAQSRPMLRLLQGDVGAGKTLVAAMALLI
AVEAGAQGAMLAPTEILARQHFETLQRLFSGLDVRIAILTGRDKGRAREATLMGLHDGSI
DILIGTHAIFQQGVEYRDLGLVVVDEQHRFGVAERMMLQAKAKTAPHLLVMTATPIPRTL
QLATHGEMDVSKLDEMPPGRQPIETSVISEERLEEIVNGLARHLSGGGQAYWVCPLVEES
EKIDLAAAGERAEALRSRFGERIGLVHGRMKGPEKDAVMARFASGELGVLVATTVIEVGV
DVPNATLIVIEHADRFGLAQLHQLRGRVGRGGGRSVCVLLRGGTLSETARARLALMRETN
DGFRIAEEDLRLRGAGEMLGTRQSGEQTFRLAPPEKFAELIGAANADARLLVDRDGGLDG
ERGQAARVALYLFERDAAVGLLRAG