Protein Info for Ga0059261_0833 in Sphingomonas koreensis DSMZ 15582

Annotation: Glycerol kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 491 transmembrane" amino acids 437 to 452 (16 residues), see Phobius details PF00370: FGGY_N" amino acids 6 to 249 (244 residues), 196.6 bits, see alignment E=5.4e-62 PF02782: FGGY_C" amino acids 260 to 446 (187 residues), 129.3 bits, see alignment E=1.7e-41

Best Hits

Swiss-Prot: 52% identical to GLPK_RHOCS: Glycerol kinase (glpK) from Rhodospirillum centenum (strain ATCC 51521 / SW)

KEGG orthology group: K00864, glycerol kinase [EC: 2.7.1.30] (inferred from 67% identity to sal:Sala_1948)

MetaCyc: 44% identical to glycerol kinase (Escherichia coli K-12 substr. MG1655)
Glycerol kinase. [EC: 2.7.1.30]

Predicted SEED Role

"Glycerol kinase (EC 2.7.1.30)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization or Glycerolipid and Glycerophospholipid Metabolism in Bacteria or MLST (EC 2.7.1.30)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.30

Use Curated BLAST to search for 2.7.1.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8W9I7 at UniProt or InterPro

Protein Sequence (491 amino acids)

>Ga0059261_0833 Glycerol kinase (Sphingomonas koreensis DSMZ 15582)
MGEKLLVIDEGTTSTRAMLFAPDGTLLASRSAELAQHYPAPGLVEHDAAEIWEKTLGCAV
AMVEAAGGADRIAAIGITNQRETIVFWDKATGEPLAPAIVWQDRRSAAICRELKEAGEEP
GVQARTGLLLDPYFSGTKIAWAMANWPQLREAGDRLAIGTVESWLVWKLTANEKRGGLHI
TDATNASRTLLMGLGSGGWSDGLIDLFGAPRAALAEIVDCAGRFGETTLFGGPIPICGMA
GDQQAATIGQACLSPGDTKATFGTGAFVLTNAGERQPASKHRLLSTVLWQLGGRRTYAIE
GSVFVAGSVVKWLRDSLGLIESAGETEVLARSVPDNGGVYFVPALTGLGAPWWEPEARGA
ISGLSLASTRAHVVRAALEAMAHQSHDLKAAFAADGADWSSLRIDGGMITNDWIAQDLAD
VLDLTVERPDFTETTALGAAMLAGVGYGLFAGLDEAAAMRGKVERFAPGMKVEARDARLA
GWKAAVEGVMA