Protein Info for Ga0059261_0652 in Sphingomonas koreensis DSMZ 15582

Annotation: Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 353 PF00072: Response_reg" amino acids 21 to 124 (104 residues), 66.7 bits, see alignment E=2e-22 PF01339: CheB_methylest" amino acids 168 to 345 (178 residues), 174 bits, see alignment E=2.4e-55

Best Hits

Predicted SEED Role

"Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61)" in subsystem Bacterial Chemotaxis (EC 3.1.1.61)

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.61

Use Curated BLAST to search for 3.1.1.61

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A1L6JBT8 at UniProt or InterPro

Protein Sequence (353 amino acids)

>Ga0059261_0652 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain (Sphingomonas koreensis DSMZ 15582)
MARNIAAAGPPPDRDGGSVRVLIVDDSVVARAVLGRMIEGMGRFRIAGSVSDVAGALAFL
ATNRADVILLDLEMPGIHGLTALPDLIAAGQGAKVLVVSSAADDGAAAAVHALALGAADT
LVKPGVGNFAGRFAAVLEDRLMRLFDTDDAAASISSHADRAPGEFDIVAVGASTGGIHAL
SQMLRAIPPSFQVPILVTQHLPASFMSYFAAQLAVLAGRPCEVAADHIRVRPGRMLVAPG
DAHLRIVRAGEGYYAVRLSHEPVASGCMPSVDPMFDSIADLFGARGLGVVLSGMGRDGAV
GAKRLIDAGGSVIVQDKASSVVWGMPGAIAESAAAVLPPDEIGRIIASQRRPG