Protein Info for Ga0059261_0381 in Sphingomonas koreensis DSMZ 15582

Annotation: Type IV secretory pathway, VirB10 components

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 410 transmembrane" amino acids 36 to 56 (21 residues), see Phobius details PF03743: TrbI" amino acids 223 to 400 (178 residues), 206.1 bits, see alignment E=2.3e-65

Best Hits

KEGG orthology group: K03195, type IV secretion system protein VirB10 (inferred from 59% identity to sch:Sphch_2743)

Predicted SEED Role

"Conjugative transfer protein TrbI" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8W8A2 at UniProt or InterPro

Protein Sequence (410 amino acids)

>Ga0059261_0381 Type IV secretory pathway, VirB10 components (Sphingomonas koreensis DSMZ 15582)
VTEPASPPDEVASKSDPEELALRANPARVTRFRRGAIVLIAGVGATALAGIGWMALKPVS
LGLIVPDDERGPVAAKTPADALAGAPSSYGEVPQLGAPLPGDLGRPILERQRQLDVAPPA
DPNADAASKAAQEAEAERQRIVAERRSARESGVMLQIAGRSATAAPAAAVAADTPQAPDA
AKPLLDPDRDPNAQALKNELVGRANRDDDTNPHALTAPPSPYTLSAGSLIAASLITGLNS
NLPGLVTAQVTENVHDSVTGRILLIPQGSRLIGSYDSVVAFGQSRALLVWQRIILPDGSS
IRIDNVPATDTQGYAGLSDRIDRHTWQLLKGVVLSTLLGVGTELSFGSSESDLVRAIRES
AQQGGSRAGDQLVTRNLNIQPTLKVRPGWPLRVVVHKDIVVARPWGGSGR