Protein Info for Ga0059261_0337 in Sphingomonas koreensis DSMZ 15582

Annotation: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 PF00501: AMP-binding" amino acids 18 to 397 (380 residues), 228.1 bits, see alignment E=1.6e-71 PF13193: AMP-binding_C" amino acids 446 to 521 (76 residues), 70.3 bits, see alignment E=2.2e-23

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A0A2M8W852 at UniProt or InterPro

Protein Sequence (539 amino acids)

>Ga0059261_0337 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II (Sphingomonas koreensis DSMZ 15582)
MLGAMQDFELRVPRLIDHAEREYGDREIVSRWFDGSETRTNWAGIARDSRKLAQALERMG
IKKGDRVATMAMNHSRHLVAWHGTIGMGGVIHTINPRLFEDQLAFIGNHAEDRVLMYDRM
FQPIVDKMKPQWKTIEHYIVFDPGSEAGAGADGPDSFEAVIGAEDGNYAWVEGDEREPCM
LCYTSGTTGNPKGVLYTHRSSVIHAMAEIQPAVFDLSTQSVVLPVVPMFHAVGWGMPFAA
PMVGVKLVMSAINEGKVLCELMNREKVTHTAGVPTVWFAMFQHMDETGDVPAYLKVVTIG
GSAAPRAMIERIMKMGARVNHAWGMTETSPIGTMGSPSADWDDLSFEAKVDKMVCQGRAP
FGVELRTVDDAGNLLPRDGESSGRLQVRGPWIIKQYFKDESGPCLTADGWFDTGDVAVLH
PDGIMQITDRAKDVIKSGGEWISSVELENAAVGCPGVAEAAAIGIHHPKWDERPLLLVIR
KPGSEVTADQIQQHLAKHVAKWWLPDEIHFVEALPHTATGKLLKTAIRDQYKGFQFAAA