Protein Info for PGA1_c09920 in Phaeobacter inhibens DSM 17395

Annotation: putative gamma-glutamyl-gamma-aminobutyrate hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 PF07722: Peptidase_C26" amino acids 6 to 223 (218 residues), 201 bits, see alignment E=2.3e-63 PF00117: GATase" amino acids 93 to 224 (132 residues), 37.5 bits, see alignment E=2e-13

Best Hits

KEGG orthology group: K07010, putative glutamine amidotransferase (inferred from 83% identity to sil:SPO2837)

Predicted SEED Role

"glutamine amidotransferase, class I"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DNQ8 at UniProt or InterPro

Protein Sequence (259 amino acids)

>PGA1_c09920 putative gamma-glutamyl-gamma-aminobutyrate hydrolase (Phaeobacter inhibens DSM 17395)
MTRPKVGIIGNSYLINDEYPAHAGGTMNSEAVAEVAGCMPLLIPSDPRFLSVEELLESFD
GFLLTGGRPNVHPNEYGEAETDAHGAFDRARDAIALPLVRACVERGQPFLGICRGFQEVN
VAMGGTLYPEIRDLPGRMNHRMPPDGTLEEKFAMRHIVELTEGGVFHRLFGAAEVMTNSL
HGQGIKAPGSRIVIDGTAPDGTPEAIYVKDAPGFTLAVQWHPEWDAANDPVSRPLFTAFG
DAVRDWAEGADRPGQRKSA