Protein Info for PGA1_c09880 in Phaeobacter inhibens DSM 17395

Annotation: aminopeptidase N

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 854 TIGR02414: aminopeptidase N" amino acids 17 to 851 (835 residues), 1080 bits, see alignment E=0 PF17900: Peptidase_M1_N" amino acids 106 to 183 (78 residues), 37.9 bits, see alignment E=4.3e-13 PF01433: Peptidase_M1" amino acids 222 to 433 (212 residues), 175.3 bits, see alignment E=3e-55 PF11940: DUF3458" amino acids 441 to 532 (92 residues), 111.2 bits, see alignment E=5.3e-36 PF17432: DUF3458_C" amino acids 537 to 853 (317 residues), 353.7 bits, see alignment E=2.3e-109

Best Hits

KEGG orthology group: K01256, aminopeptidase N [EC: 3.4.11.2] (inferred from 80% identity to sit:TM1040_0706)

Predicted SEED Role

"Membrane alanine aminopeptidase N (EC 3.4.11.2)" (EC 3.4.11.2)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EVB1 at UniProt or InterPro

Protein Sequence (854 amino acids)

>PGA1_c09880 aminopeptidase N (Phaeobacter inhibens DSM 17395)
MKDAAPATAPETFYLKDYKPFGFEVEAVELTFKLAPNSTRVLSKIRFSPKDNAADPRFFL
HGEALKLISAKIDGAPVTPELIAGGLICDTPDTPFTWEAEVEIAPAANTALEGLYMSSGM
YCTQCEAEGFRKITYYPDRPDVMSTFSVRIEGDETVLLSNGNPAGSGEGWAEWHDPWPKP
AYLFALVAGDLVNHPDRFTTRSGKDVELNIWVRPGDEGKCAFGMEALKKSMKWDEDVYGR
EYDLDIFNIVAVDDFNMGAMENKGLNIFNSSCVLASPETSTDANFERIEAIIAHEYFHNW
TGNRITCRDWFQLCLKEGLTVFRDAQFTADMRSEPVKRIEDVIALRARQFPEDNGPLAHP
PRPEQFQEINNFYTATVYEKGAEVIGMLKRLVGDDNYDKALDLYFDRHDGQACTIEDWLR
VFEDATGRDLSQFKLWYSQAGTPRVKVSEAYANGTYTLTLAQSTPPTPGQPDKAPRVIPI
TIGLLSPNGDEIRATEVLELTEAEQSFTFDGLAAKPVPSILREFSAPVILKRESTNAERA
FLLAHDTDPFNRWEAGNALATETRVTMVTEGAAPDAAYLDALEKLVRDDTLDPAFRALVL
SPPSQSEIAQTLHDRGVTPDPQKIYDAAETFAQTLAQQLETSLPRLYAATTVDGPYQPDA
HGAGLRALNGRILSLLTRLDGGEQAARQYQAADNMTQQYAALAALMKAENGERQSQAFFD
QWQNDRLVMDKWFALQVACAAPDAAAKVATDLTRHALFDMKNPNRFRAVMGALAGNHAGF
HHASGAGYQLLAENLIALDNLNPQTTARMCAAFQTWKRYDSTRQALIRVELERILATEGL
SRDTHEMVSRILQG