Protein Info for HP15_938 in Marinobacter adhaerens HP15

Annotation: spermidine/putrescine ABC transporter, permease protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 293 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 55 to 76 (22 residues), see Phobius details amino acids 81 to 101 (21 residues), see Phobius details amino acids 107 to 126 (20 residues), see Phobius details amino acids 129 to 149 (21 residues), see Phobius details amino acids 161 to 183 (23 residues), see Phobius details amino acids 205 to 229 (25 residues), see Phobius details amino acids 260 to 281 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 93 to 279 (187 residues), 50.9 bits, see alignment E=8.2e-18

Best Hits

Swiss-Prot: 62% identical to POTH_ECOLI: Putrescine transport system permease protein PotH (potH) from Escherichia coli (strain K12)

KEGG orthology group: K11075, putrescine transport system permease protein (inferred from 92% identity to maq:Maqu_2137)

MetaCyc: 62% identical to putrescine ABC transporter membrane subunit PotH (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotH (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PEZ7 at UniProt or InterPro

Protein Sequence (293 amino acids)

>HP15_938 spermidine/putrescine ABC transporter, permease protein (Marinobacter adhaerens HP15)
MLFNRRVVFGIPFLWLLLFFLLPFALVLKISLTSAVMAIPPYEPVFRWVDNTLSVVVNIG
NYLFLLSDSLYFAAYWGSVKTAFLATVMCLLIGYPMAYAMARTPKHWQLVLLLMVMLPSW
TSFLIRVYAWMGILGNQGLLNSFLMWLGFIDQPLKMLNTNFAVVLGIVYAYLPFMVLPIY
TNLVKLDVRLLEAASDLGCRSLTTFWAITLPLSKAGILAGSMLVFIPAVGEFVIPELLGG
PDTLMIGKVLWEEFFNNRDWPVASALAIVMLLLLLVPIVLFHRFQAREMEKHG