Protein Info for PGA1_c08750 in Phaeobacter inhibens DSM 17395
Annotation: sarcosine oxidase subunit beta
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 70% identical to SOXB_RHIME: Sarcosine oxidase subunit beta (soxB) from Rhizobium meliloti (strain 1021)
KEGG orthology group: K00303, sarcosine oxidase, subunit beta [EC: 1.5.3.1] (inferred from 85% identity to sit:TM1040_2147)MetaCyc: 52% identical to sarcosine oxidase beta subunit (Corynebacterium sp.)
RXN-22742 [EC: 1.5.3.24]
Predicted SEED Role
"Sarcosine oxidase beta subunit (EC 1.5.3.1)" in subsystem Choline and Betaine Uptake and Betaine Biosynthesis (EC 1.5.3.1)
MetaCyc Pathways
- glycine betaine degradation I (7/8 steps found)
- creatinine degradation I (2/4 steps found)
- creatinine degradation II (1/5 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 1.5.3.1
Use Curated BLAST to search for 1.5.3.1 or 1.5.3.24
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See I7EXJ9 at UniProt or InterPro
Protein Sequence (417 amino acids)
>PGA1_c08750 sarcosine oxidase subunit beta (Phaeobacter inhibens DSM 17395) MRFSGWRVLREGLTGNRGWQGHWRDPDPKPEYDAVIIGGGGHGLATAYYLARDHGMTNIA VLERGYIGGGNVGRNTTIVRANYYLPGNSEFYSHSLKLWEGLEQDLNYNAMMSQRGILNV FHNDAQRDSAVRRANAIINQGDDAEILSRDQLREMVPLLNYANNRFPIQGALLQRRAGTA RHDAVAWGFARGADQRGVDILQNCEVTGIRTEGGKVIGVETSRGLIRAGKVAMAAAGRSS QVAAMAGLTLPIESHVLQAFVSEGLKPIIDHVLTFAEGHLYISQSDKGGLVFGSYLDLYA SYAARGNLPMVEHTMEACMAMLPAIGKARLLRSWGGIMDMTPDGSPIIDRTSIEGLYLNA GWCYGGFKATPASGQCYAHLIATDRPHEAAAAFRLERFETGHGLMDEEATGAQHNLH