Protein Info for HP15_834 in Marinobacter adhaerens HP15

Annotation: glutathione-dependent formaldehyde-activating, GFA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 137 PF04828: GFA" amino acids 1 to 111 (111 residues), 87.1 bits, see alignment E=4.5e-29

Best Hits

KEGG orthology group: None (inferred from 87% identity to maq:Maqu_2194)

Predicted SEED Role

"FIG00783930: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PR63 at UniProt or InterPro

Protein Sequence (137 amino acids)

>HP15_834 glutathione-dependent formaldehyde-activating, GFA (Marinobacter adhaerens HP15)
MYTGRCLCGDICFEYDGPIGPVALCHCSQCRRAHGSAFSASAPVQKVRFRFVTGEDKITE
FESRPGKYRGFCSRCGSQLYSRVDAIPGILRLRVGCINEPLNKGAAHHVFVGSKSDWFEI
TDELPQFEKTERTNDPH