Protein Info for Psest_0076 in Pseudomonas stutzeri RCH2

Annotation: NhaP-type Na+/H+ and K+/H+ antiporters

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 33 to 51 (19 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 92 to 115 (24 residues), see Phobius details amino acids 121 to 140 (20 residues), see Phobius details amino acids 161 to 180 (20 residues), see Phobius details amino acids 194 to 214 (21 residues), see Phobius details amino acids 235 to 261 (27 residues), see Phobius details amino acids 310 to 325 (16 residues), see Phobius details amino acids 333 to 349 (17 residues), see Phobius details amino acids 355 to 373 (19 residues), see Phobius details amino acids 384 to 404 (21 residues), see Phobius details amino acids 415 to 434 (20 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 15 to 268 (254 residues), 89.4 bits, see alignment E=1.1e-29 amino acids 336 to 440 (105 residues), 35 bits, see alignment E=3.8e-13

Best Hits

KEGG orthology group: None (inferred from 94% identity to psa:PST_4134)

Predicted SEED Role

"sodium/hydrogen exchanger family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GH94 at UniProt or InterPro

Protein Sequence (454 amino acids)

>Psest_0076 NhaP-type Na+/H+ and K+/H+ antiporters (Pseudomonas stutzeri RCH2)
MNFLEWMAVLGVLLLILALASAFLRWLPITTSLIYLGFGVLIGQLGVGLWEMEFLHIAGW
MEHLTEVAVLVSLFVSGLKLRMPLRHPAWKSAYVLAGPVMLACIGGVTLLCHYVFGLSWG
VAVLIGAILAPTDPVLASLVQVNDARDSDRLRYGLSGEAGFNDGTAFPFVVFGLMLIAQG
QLEADWVGEWALHRLLWAVPAGLLIGFLLGKLVGRVAIYLRARHTDTAMSPNDSLALALI
ALAYVGAELAGAWGFLAVFAAGLGLRHAEMAAADDSETPSEELINDAVPHLAEGGLAPRA
LSLDDRQLGQPRVAAGVLMGDVLAFGGQLERSLEVLLVTMLGVLVSVHWDWRAVPLGLAL
FLLIRPLSVMLLMPRRYLDRGQCLTAGWFGIRGIGSLYYLSYAVTHGLLPEEAHTIIGLV
LSVVALSIVLHGLSTQPLLRRYERSRGETPDGQG