Protein Info for Psest_0749 in Pseudomonas stutzeri RCH2

Annotation: Transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 236 PF00440: TetR_N" amino acids 47 to 91 (45 residues), 51.2 bits, see alignment 8.3e-18 PF08362: TetR_C_3" amino acids 94 to 236 (143 residues), 192.7 bits, see alignment E=3e-61

Best Hits

Swiss-Prot: 56% identical to RUTR_ECO57: HTH-type transcriptional regulator RutR (rutR) from Escherichia coli O157:H7

KEGG orthology group: K09017, TetR/AcrR family transcriptional regulator (inferred from 93% identity to psa:PST_3596)

Predicted SEED Role

"Transcriptional regulator RutR of pyrimidine catabolism (TetR family)" in subsystem Pyrimidine utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GHT2 at UniProt or InterPro

Protein Sequence (236 amino acids)

>Psest_0749 Transcriptional regulator (Pseudomonas stutzeri RCH2)
MTDQPPVPPRKRLTASKTPRLKGAARVPSASAQDRRLRMIESKRASILQAALELFSRFGL
HGTSLDQVATQADVSKTNLLYYFGSKEELYTSVLRQLLEVWLQPLQAFSVEQDPVEAIRD
YLRVKLELSRDHPAESRLFCMEIMQGAPLLLGELQQPLHDLVESKVAVIQAWIDAGTLAA
IAPHHLIFSLWATTQHYADFRVQVEAVAGKTLDDPAFFEETLKSLQALILDGVRPR