Protein Info for PGA1_c07300 in Phaeobacter inhibens DSM 17395

Updated annotation (from data): Inositol transport system sugar-binding protein
Rationale: Specific phenotype on inositol and cofit with other nearby components (SEED_correct)
Original annotation: ABC-type sugar transport system, periplasmic component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 316 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 39 to 282 (244 residues), 138.9 bits, see alignment E=2.4e-44 PF00532: Peripla_BP_1" amino acids 40 to 238 (199 residues), 35.3 bits, see alignment E=9.3e-13

Best Hits

KEGG orthology group: K02058, simple sugar transport system substrate-binding protein (inferred from 88% identity to sit:TM1040_3343)

Predicted SEED Role

"Inositol transport system sugar-binding protein" in subsystem Inositol catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EJU1 at UniProt or InterPro

Protein Sequence (316 amino acids)

>PGA1_c07300 Inositol transport system sugar-binding protein (Phaeobacter inhibens DSM 17395)
MTSIFKTFMLATTVAAAPMMLATTASAEGEKYILVSHAPDSDSWWNTIKNGIALAGEQMN
VEVEYRNPPTGDLADMARIIEQAAASGPNGIITTLSDYDVLSGPIKAAVDSGVDVIIMNS
GTPDQAREVGALMYVGQPEYDAGHAAGMRAKADGVGSFLCVNHYISSPSSTERCQGFADG
LGVDLGDQMIDSGQDPAEIKNRVLAYLNTNPETDAILTLGPTSADPTLLALDENGMAGDI
YFGTFDLGEEIVKGLKSGVINWGIDQQPFLQAYLPVVVLTNYHRYGVLPGNNINSGPGFV
TKDGLEKVEEFAGEYR