Protein Info for PGA1_c07170 in Phaeobacter inhibens DSM 17395

Annotation: acetate operon repressor-like protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 270 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF09339: HTH_IclR" amino acids 4 to 50 (47 residues), 37 bits, see alignment 2.4e-13 PF01614: IclR_C" amino acids 73 to 236 (164 residues), 72.8 bits, see alignment E=2.7e-24

Best Hits

KEGG orthology group: None (inferred from 70% identity to sil:SPOA0268)

Predicted SEED Role

"Transcriptional regulator, IclR family" in subsystem Homogentisate pathway of aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EX59 at UniProt or InterPro

Protein Sequence (270 amino acids)

>PGA1_c07170 acetate operon repressor-like protein (Phaeobacter inhibens DSM 17395)
MQDRQILILEAVASSASPVSASELARMTATPRASLYRHIAALLECGFLEETETGSRYVLG
LRFVKIALTGKSDTHVINAVSAVLQRVVKDLGETAFLARYRGGRVDLIHTQVPADPSVPY
IYPGLGVRPVHACSSAKAIAAFLAPELQEDLIDTLPMRFTDKTRTDPDQIARELQQVRRY
GYATCDGEIDIGVTSVAVPIIVDRLGAIFSMGVVGPTSRITPAIQPRILPILTKQAVHAA
AAIQHCSVVEAETTNAHSLAAAKERASQQH