Protein Info for PGA1_c06460 in Phaeobacter inhibens DSM 17395

Annotation: Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details PF05036: SPOR" amino acids 30 to 90 (61 residues), 22.9 bits, see alignment E=1.3e-08 PF01471: PG_binding_1" amino acids 168 to 223 (56 residues), 42.1 bits, see alignment 1.2e-14 PF13365: Trypsin_2" amino acids 398 to 527 (130 residues), 45.2 bits, see alignment E=2.6e-15

Best Hits

KEGG orthology group: None (inferred from 65% identity to sit:TM1040_2313)

Predicted SEED Role

"FIG313892: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7DMN8 at UniProt or InterPro

Protein Sequence (592 amino acids)

>PGA1_c06460 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain (Phaeobacter inhibens DSM 17395)
MKTLIATLALALMTLASAFSGVAHAQQSSQDTVWIQVAARASLREAQAEAQNFAAQLPDV
SGFALGGGWYGIVLGPYARTDADRVLQVYRAEGQIPRDSFIAFGNNLGNQFYPTAATANT
EPQPTVDSPVLEPIDPAVATEAPTEPVQTALPDETPAEARRSESRLTRDERKDLQIALKA
AGFYTSTIDGAFGRGTRGSMSDWQSARGYAPTGVLTTAQRQALMDEYNAPLISVGMAPLT
DTKAGIALKIPAGEVTFDRYESPFALFKSSGDLGAQVLLISQPGDKRTLYGLYDIMQTLK
IVPLEGPRQRSGNSFTLEGRGNGIVSYTEARLANGEIKGFTLVWPMGDDDRRARVLAEMQ
TSFERIDGVLDPAAGADAPQNVDLVSGLDVRKPRLSRSGFYVDAKGSVVTTSDVVAGCAR
VTLDHEYQAEVAFNDSAAGIAVLRPVEPLAPMAVANLASASARLQSDIAVSGFSYEGVLG
APSLSWGSLQDVKDLTGNAGVSRLQLTSQPGDAGGPVLTTDGAVQGMLLSQSKSATQLPE
GVSFAANAESLRSALSSAGVTPKDASAGATALPVGALTRQASGMTVLVSCWE