Protein Info for Psest_0591 in Pseudomonas stutzeri RCH2

Annotation: heavy metal sensor kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 457 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details TIGR01386: heavy metal sensor kinase" amino acids 3 to 452 (450 residues), 423.9 bits, see alignment E=4.5e-131 PF21085: CusS" amino acids 4 to 152 (149 residues), 30.8 bits, see alignment E=6e-11 PF00672: HAMP" amino acids 177 to 229 (53 residues), 32.8 bits, see alignment 1.4e-11 PF00512: HisKA" amino acids 235 to 300 (66 residues), 57.6 bits, see alignment E=2.1e-19 PF02518: HATPase_c" amino acids 343 to 453 (111 residues), 81 bits, see alignment E=1.8e-26

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GIF1 at UniProt or InterPro

Protein Sequence (457 amino acids)

>Psest_0591 heavy metal sensor kinase (Pseudomonas stutzeri RCH2)
MGKVSLTSRMAIAFMLVVTVVLLAAAISFNYFCQLHFERKDAQVLNEKAAAVERTLLNSS
AFGPETASRIDAVIEHSFGFATAVVVDGKTVYSHHNLSESLLPLVTDIQEERWTVSFGGH
QYSGITRKVNRWVEGQDTVIYLALDVTHRIHFFDMIQQWFAYTLVVSALLSGALGVVLIR
KGLKPIDELSKTSSTVTAHCLDTRIPTESVPGELHELVDNFNEMLSRLDDSFLRLSGFSA
DIAHELRTPLNSMLTQMEVALLRDRENTDYKDILYSALEELRRMSKMVDDMLFLAKADNG
KITPNAEDASMAEITASVIEYYELAAEDKKVEIALSGDGSVHGDKSMLRRAVSNIVSNAV
RYAEEGSTISVEISESGGSVCTAISNRGTTIPAELQARVFDRFYRVDTARREGTTMNAGL
GMAITRSIVEAHKGRIACESAEGHTTFTMTLPKLMSS