Protein Info for HP15_p187g38 in Marinobacter adhaerens HP15
Annotation: RND type efflux pump involved in aminoglycoside resistance (AdeT)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 39% identical to ADET1_ACIBA: Probable solute-binding protein AdeT1 (adeT1) from Acinetobacter baumannii
KEGG orthology group: None (inferred from 78% identity to maq:Maqu_2798)Predicted SEED Role
"FIG00785198: hypothetical protein"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See E4PS00 at UniProt or InterPro
Protein Sequence (343 amino acids)
>HP15_p187g38 RND type efflux pump involved in aminoglycoside resistance (AdeT) (Marinobacter adhaerens HP15) MTVMESITMRKLMTAVALTCAAPLASANTLSVCVFDVIGANGDVFNLMRDYALNLKAEGV DLELKPYTDEGVAVGDFNAGQCDAVAATDLRTRPFNRFTGSVSAVGALPSYENLETLLAT LAQPKAASLMKEGGFEVMGIFPVGAGYLFVNDRSIDTAGELAGKRMATLDYQKDAIHMVN YVKATVVPSDITNFAGKFNNGSVDTAYAPAFAYEALELYKGLEPDGGVVDYPLAQLTAQI IVRDEALADETAQKAREIAFSMYPQVMDLIASQEAAIPDDKWIRIPDADIRGYQEMFREN RLEMRDGVNSAPSVYHPKMLTLMANIRCASNPSASECTADNRE