Protein Info for HP15_p187g37 in Marinobacter adhaerens HP15

Annotation: integral membrane protein, transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 transmembrane" amino acids 19 to 39 (21 residues), see Phobius details amino acids 149 to 168 (20 residues), see Phobius details amino acids 188 to 207 (20 residues), see Phobius details amino acids 221 to 239 (19 residues), see Phobius details amino acids 251 to 275 (25 residues), see Phobius details amino acids 283 to 306 (24 residues), see Phobius details amino acids 318 to 340 (23 residues), see Phobius details amino acids 345 to 363 (19 residues), see Phobius details amino acids 375 to 402 (28 residues), see Phobius details amino acids 414 to 433 (20 residues), see Phobius details amino acids 455 to 475 (21 residues), see Phobius details amino acids 481 to 499 (19 residues), see Phobius details amino acids 520 to 545 (26 residues), see Phobius details amino acids 565 to 594 (30 residues), see Phobius details amino acids 606 to 623 (18 residues), see Phobius details amino acids 657 to 679 (23 residues), see Phobius details PF06808: DctM" amino acids 259 to 675 (417 residues), 72.7 bits, see alignment E=1.3e-24

Best Hits

KEGG orthology group: None (inferred from 78% identity to maq:Maqu_2797)

Predicted SEED Role

"TRAP-type C4-dicarboxylate transport system, large permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRZ9 at UniProt or InterPro

Protein Sequence (681 amino acids)

>HP15_p187g37 integral membrane protein, transporter (Marinobacter adhaerens HP15)
MTSRATGTSGALYPVHKVHGVVLLLLLLFTLLLGMGNSLHSRLLLIGEQTWPNYYLLDPA
ATEPTCSLEIDVDAEVQKRIDAYEPDPDALFSSPPNAQAIRESLLQNLELCEQRFEQYRL
TQEAVTPALTVYKTIEQGLAETLLENIELTKFLFIAMFALAAAIAAFDTDHIALRLPRNR
AEWRLSQGVQLIVNGLMVLSLFAYLDRLAVSPGTESTQTLQYGWSIVFILFMAINLIRLA
KVPAHLNTGSLTLSSGLVLPLYCVMGLIAMTYFVVVDEYQSGLAIYFGIMTNLSSMFINI
GLYVLVGMMLKQTRIPELLFNALKPFNLPAPMLASVIIFATAFPTAFTGASGIFILAVGG
VVYDELRRAGAGRQLSLATTAMSGSLGVVLNPCLLIVVVAALNKEVTTSEMYGWGFWVFM
MSATLFSIVVCKTQGNWRPSPQKGAAKEALRRLGPLTPYVIGVVIVIGLIWLLLGLQFNE
YSAPLILPLVMLALVFLDTKAESRQTKRSRFSLFWRRSTLAASDSAVHIGALLALIGFSI
CLGGILERSDIVHALFPEDLTSPWIAMLVIVVMLTIIGMVMDPFGAVILVSATVAQPAIQ
IGIDPLHFWIVCLVAFELGYLSPPVALNHLLTRQVVGESEVLAAEKRGSFWRRYERLLLP
LSVMAPTLLFVAFVPLLFYAL