Protein Info for HP15_p42g47 in Marinobacter adhaerens HP15

Annotation: conjugal transfer protein TrbG/VirB9/CagX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details TIGR02775: P-type conjugative transfer protein TrbG" amino acids 71 to 286 (216 residues), 297.4 bits, see alignment E=2.3e-93 PF03524: CagX" amino acids 83 to 298 (216 residues), 176.9 bits, see alignment E=2.4e-56

Best Hits

KEGG orthology group: K03204, type IV secretion system protein VirB9 (inferred from 74% identity to bam:Bamb_6630)

Predicted SEED Role

"Conjugative transfer protein TrbG" in subsystem Type 4 secretion and conjugative transfer

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PRV7 at UniProt or InterPro

Protein Sequence (301 amino acids)

>HP15_p42g47 conjugal transfer protein TrbG/VirB9/CagX (Marinobacter adhaerens HP15)
MKKQFSAVILGAAMLVPSLATVAHANGLEDKYFTNDNPTLTQQERQALAIAQRWQAGGSN
GGIRPFTGRNGAIQFVFGAQSPSVVCAVLQVCDVALQPGEYVNSIQLGDTARWNVEPAIS
GTGAGETQHLLIKPMDVGLETSLVVTTDRRVYHIRLRSHRTEYMPQVAFTYPEDALAKWD
MVRSRERQHREDNTIPRTREYLGDLSFDYDVSGSASWKPVRVFNDGHKTIIQMPRAMQQT
EAPTLLVVRKDGGLFSDPETVMVNYRVQGDRYIVDTVFNKAILISGVGSSQDKITITKGD
D