Protein Info for HP15_413 in Marinobacter adhaerens HP15

Annotation: pilus (MSHA type) biogenesis protein MshL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 570 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details PF07655: Secretin_N_2" amino acids 159 to 249 (91 residues), 93.9 bits, see alignment E=7.1e-31 TIGR02519: pilus (MSHA type) biogenesis protein MshL" amino acids 243 to 531 (289 residues), 264.9 bits, see alignment E=3.5e-83 PF00263: Secretin" amino acids 354 to 531 (178 residues), 134 bits, see alignment E=4.3e-43

Best Hits

KEGG orthology group: K12282, MSHA biogenesis protein MshL (inferred from 76% identity to maq:Maqu_0753)

Predicted SEED Role

"MSHA biogenesis protein MshL" in subsystem Mannose-sensitive hemagglutinin type 4 pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PMP9 at UniProt or InterPro

Protein Sequence (570 amino acids)

>HP15_413 pilus (MSHA type) biogenesis protein MshL (Marinobacter adhaerens HP15)
MTTIKITGALALSLVLTACSNNPLMRSATATSTDAADAIDQSLEEATQPKPAAPASTEAS
APLPADVSAALLPSLSGGADLDERFDVNARGVPAASFFESLVEGTRYNVVVHPDVTTSID
LRLGDVTVPEVMDIAGDLYGLDIRRNGRLFRVQADQVQTRMFPIDYLHFKRKGGSETRVS
SGQVTGARSGSSGNSNSNGDSTGSGETRNLVGTTISTETASDFWKDIQSALSMIVGGGDG
QQVIVNPGAGLVMVRAGSEDLRMVEEYLRRTELIMQRQVILEAKILEIALNEGYQQGINW
SDIQSASSITASDGLPEDFTAQALAGQVIQTSDIGGLFSASVRAGDFTGLIELLGKQGNV
QILSSPRISTVNNQKAVIKVGTDEFFCHRYDFDDNNSAVTATDSTSTSVELTPFFSGISL
DVTPQISESGVITLHVHPSVSEVTDQEKVITIGERDVTLPLASSTVRETDSVIRAESGQI
VVIGGLIQNSSEDNNSAVPFFSEIPLVGELFKQRRFQSRKSELVILLRPVVAGTPEMNAD
VSASRERMNVLRELLQSSESVTPEPEKAVR