Protein Info for Psest_4320 in Pseudomonas stutzeri RCH2

Annotation: Zn-dependent oligopeptidases

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 683 PF19310: TOP_N" amino acids 51 to 147 (97 residues), 89.7 bits, see alignment E=1.3e-29 PF01432: Peptidase_M3" amino acids 225 to 677 (453 residues), 501.3 bits, see alignment E=4e-154

Best Hits

Swiss-Prot: 58% identical to OPDA_SALTY: Oligopeptidase A (prlC) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K01414, oligopeptidase A [EC: 3.4.24.70] (inferred from 96% identity to psa:PST_4156)

MetaCyc: 59% identical to oligopeptidase A (Escherichia coli K-12 substr. MG1655)
Oligopeptidase A. [EC: 3.4.24.70]

Predicted SEED Role

"Oligopeptidase A (EC 3.4.24.70)" in subsystem Protein degradation (EC 3.4.24.70)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.70

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See L0GU08 at UniProt or InterPro

Protein Sequence (683 amino acids)

>Psest_4320 Zn-dependent oligopeptidases (Pseudomonas stutzeri RCH2)
MSANNPLLQDFDLPPYSEIRPEHVEPAIDTILGDNRVAIQELLSRPADSLDWQTLVVGLD
ELNDRLARAWGPVSHLNSVCNSPELRTAYEACLPKLSAYYTELGQNRALFEAYQALAASP
AAAGFEVAQKTILEHSLRDFRLSGIDLPPVEQQRFGAIQMKLAELGSKFSNQLLDATQGW
TRHITDESLLAGITDSAKAQMAEAAKAKDLDGWLITLEFPSYYAVMTYADNRDLREEVYA
AYCTRASDQGPNAGQFDNGPVMAEILELRHELAGLLGYGNFAELSLATKMAESTEQVLSF
LRDLAVRSKPFAERDLAELRAFAAEQGLDDLQSWDLGYYAEKLRQQRYSLNQEELRAYFP
IDKVLSGLFCIVQRLYGIDIHELEQFDGWHPEVRLFEISENGQHVGRFFFDLYARPNKRG
GAWMDGARDKRRTALGTLQTPVANLVCNFTPPVGERPALLTHDEVTTLFHEFGHGLHHLL
TQVEHAGASGINGVAWDAVELPSQFMENWCWDPEGLAHISGHYQTGERLPQDKLDMMLAA
KNFQSGMMMARQLEFSLFDFELHATHGDGRSVLQVLEHIRDEVSVMRPPAYNRFPNSFAH
IFSGGYAAGYYSYKWAEVLSSDAFSRFEEEGVFNSETGRAFREAILARGGSQEPMVLFVD
FRGREPSIDALLRHLGLVAEAAA