Protein Info for HP15_4171 in Marinobacter adhaerens HP15

Annotation: transcriptional regulator of molybdate metabolism, LysR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 393 PF12727: PBP_like" amino acids 162 to 350 (189 residues), 134.9 bits, see alignment E=1e-43

Best Hits

KEGG orthology group: None (inferred from 36% identity to hdn:Hden_0222)

Predicted SEED Role

"Periplasmic molybdate-binding domain" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See E4PMM7 at UniProt or InterPro

Protein Sequence (393 amino acids)

>HP15_4171 transcriptional regulator of molybdate metabolism, LysR family (Marinobacter adhaerens HP15)
MHTCSYLVVLNATKEPYHSLKRSPICMAIPKLSVFPAWAIHTTHASQLDPAIFPLLQAVR
ETEKLTEAAKFAGISYRHAWNLLHQLGEALEFPIVVRQRGRGTRLSDLGERVLLAEQRVR
ARLGPQLDSMASEINDEIQKVVAGRNAVLRINASHGYAISLLPQHNDQVEINLQYRNPQE
ALLDLLNGRCDISSFHFPTCPFLAKRVLDHYESELNRAQLKLIRFVKRKEGLMMKPSVGP
LKSLKELTESNALFIRRDTHSGTRILFDLLMEREKLTLGAVNCTSHYEYTHTAIAACVAA
GMADVGFGVEAAANQFGLSFSELAEEHYLLACREENLKLATVQDLIGLIQSKSVLDSVEN
LPGYCPDSPGEITTFDELLSENQGYVPSNHVAP