Protein Info for Psest_4291 in Pseudomonas stutzeri RCH2

Annotation: agmatine deiminase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR03380: agmatine deiminase
  • amino acids 6 to 364 (359 residues), 569.8 bits, E=1.1e-175
• PF04371: PAD_porph
  • amino acids 15 to 363 (349 residues), 424.3 bits, E=1.6e-131

Best Hits

Swiss-Prot: 91% identical to AGUA_PSEU5: Agmatine deiminase (aguA) from Pseudomonas stutzeri (strain A1501)

KEGG orthology group: K10536, agmatine deiminase [EC: 3.5.3.12] (inferred from 91% identity to psa:PST_0060)

MetaCyc: 77% identical to agmatine deiminase subunit (Pseudomonas aeruginosa)
Agmatine deiminase. [EC: 3.5.3.12]

Predicted SEED Role

"Agmatine deiminase (EC 3.5.3.12)" in subsystem Arginine and Ornithine Degradation or Polyamine Metabolism (EC 3.5.3.12)

MetaCyc Pathways

• L-arginine degradation IV (arginine decarboxylase/agmatine deiminase pathway) (3/3 steps found)
• putrescine biosynthesis II (3/3 steps found)
• superpathway of polyamine biosynthesis II (5/8 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Urea cycle and metabolism of amino groups

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.3.12

Sequence Analysis Tools

See L0GTQ3 at UniProt or InterPro

Protein Sequence (368 amino acids)

>Psest_4291 agmatine deiminase (Pseudomonas stutzeri RCH2)
MTTLTTTPRTDGYFMPAEWAPHSQTWMVWPQRPDNWRDNGSPAQAAFTAVAKAIARFEPV
TVCASAEEYLAARAALNDPRIRVVEISTDDAWVRDTGPTFIVDDNGGLRGVDWTFNAWGG
EDGGLYADWQRDDEVARKILEIEYCDRYRTEGFVLEGGSIHVDGQGTLITTEECLLNRNR
NPQLTREQIEAVLREHLAVDSIIWLPHGLFNDETDGHVDNFCCFVRPGEVLLAWTDDAND
PNFERCQAAMAVLQNARDAKGRALTVHKMPIPGPLHATAEECAGVVALDGSQPRDPSVRL
AGSYVNFLIVNGGIIAPAFGDPLDAEAERILAQVFPEHQVVMAPGREILLGGGNIHCITQ
QQPAPLLR