Protein Info for PGA1_c04290 in Phaeobacter inhibens DSM 17395

Annotation: phosphonates transport ATP-binding protein PhnL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 TIGR02324: phosphonate C-P lyase system protein PhnL" amino acids 1 to 218 (218 residues), 316.3 bits, see alignment E=5.1e-99 PF00005: ABC_tran" amino acids 25 to 174 (150 residues), 99.1 bits, see alignment E=1.7e-32

Best Hits

Swiss-Prot: 58% identical to PHNL_ECOLI: Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL (phnL) from Escherichia coli (strain K12)

KEGG orthology group: K05780, putative phosphonate transport system ATP-binding protein (inferred from 85% identity to sit:TM1040_3698)

MetaCyc: 58% identical to ATP-binding cassette protein PhnL (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Phosphonates transport ATP-binding protein PhnL" in subsystem Alkylphosphonate utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See I7EJ36 at UniProt or InterPro

Protein Sequence (227 amino acids)

>PGA1_c04290 phosphonates transport ATP-binding protein PhnL (Phaeobacter inhibens DSM 17395)
MIELQNVSKSFTLHNQGGAVIPVMEGASLTVAAGECIGLTGASGAGKSTLMRVIYGNYLA
ASGKVMIGGVDVARAAPREILALRRETLGYVSQFLRVVPRVPTLDVVAEPLLAVGVDLAV
ARDRAATLLAGLNIPERLWQLSPTTFSGGEQQRVNIARGFAHTYPAMLLDEPTASLDAQN
RATVLSLIEEAKARGAAIIGIFHDEAAREQVCDRFVDVSAFTPKAAA